GNB2L1 and IFNR

Number of citations of the paper that reports this interaction (PMID 12960323)
10

Data Source:
BioGRID (pull down)

		GNB2L1	IFNR
Gene Name		guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	interferon production regulator
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Phagocytic Cup Nucleus Cytoplasm Mitochondrion Cytosol Cytoskeleton Small Ribosomal Subunit Dendrite Midbody Neuronal Cell Body Perikaryon Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase C Binding Receptor Binding Protein Binding Ion Channel Inhibitor Activity Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Enzyme Binding Protein Phosphatase Binding Protein Tyrosine Kinase Inhibitor Activity Receptor Tyrosine Kinase Binding Protein Complex Scaffold SH2 Domain Binding Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	Osteoblast Differentiation Positive Regulation Of Protein Phosphorylation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Cycle Gastrulation Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Translation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Positive Regulation Of Cell Migration Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Homooligomerization Regulation Of Protein Localization Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Rhythmic Process Negative Regulation Of Phagocytosis Regulation Of Cell Division Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Cell Cycle Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Regulation Of Establishment Of Cell Polarity Positive Regulation Of Gastrulation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		86 interactors: ADH1B ADRB2 AGTRAP AR AURKB BCL2L11 CCNA1 CDKN1A CHERP CSF2RB DDX19B DGCR14 DNM1 DYNLL1 EIF6 EPOR FBXW7 FYN GABRB3 GNB1 GOLM1 GRAP2 GRIN2B HABP4 HIF1A HNRNPH2 IFNAR1 IFNAR2 IFNR IGF1R IK IL2RB IL4R IL7R INSR ITGB1 ITGB2 ITGB5 ITGB7 JAK1 LARP4B LRP12 MAPK6 MKRN2 NFATC1 NR3C1 NSMAF PABPC1 PDE4D PLCG1 PLEC PRKAB2 PRKCA PRKCB PRKCD PRKCE PRKD1 PRPF31 PTN PTOV1 PTPRM RASA1 RASA3 RB1 RHOA SAT1 SLC27A6 SLC6A3 SRC SREK1 ST7 STAT1 STAT3 SUMO4 SYT1 TARDBP TBXA2R TCEB1 TCEB2 TNFRSF1A TP63 TP73 TSC22D4 TUBB TYK2 WDR83	1 interactors: GNB2L1
Entrez ID		10399	3466
HPRD ID		01503
Ensembl ID		ENSG00000204628
Uniprot IDs		E9KL35 P63244
PDB IDs		3J3A 4AOW
Enriched GO Terms of Interacting Partners?		Signaling Cell Communication Cellular Response To Stimulus Signal Transduction Response To Stimulus Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Intracellular Signal Transduction Response To Organic Substance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction Response To External Stimulus Defense Response Viral Process Response To Stress Immune System Process Regulation Of Immune Response Regulation Of Body Fluid Levels Regulation Of Cell Proliferation Regulation Of Immune System Process Response To Abiotic Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization Positive Regulation Of Signal Transduction Regulation Of Cellular Localization Response To Cytokine Regulation Of Cell Death Regulation Of Cellular Process Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Platelet Activation Innate Immune Response Immune Response Regulation Of Phosphorylation Blood Coagulation Regulation Of Apoptotic Process Hemostasis Regulation Of Protein Phosphorylation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Cycle Positive Regulation Of Transport Peptidyl-tyrosine Autophosphorylation Cellular Process Neurotrophin TRK Receptor Signaling Pathway Developmental Process Regulation Of Angiogenesis Positive Regulation Of Cellular Metabolic Process	Positive Regulation Of CAMP Catabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Gastrulation Positive Regulation Of Protein Homooligomerization Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Mitochondrial Depolarization Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Phagocytosis Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Mitochondrial Depolarization Positive Regulation Of Protein Oligomerization Negative Regulation Of Oxidative Stress-induced Cell Death Regulation Of Protein Oligomerization Regulation Of Response To Reactive Oxygen Species Positive Regulation Of Embryonic Development Regulation Of Gastrulation Regulation Of Membrane Depolarization Regulation Of Establishment Of Cell Polarity Negative Regulation Of Protein Kinase B Signaling Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Endocytosis Regulation Of Cellular Response To Oxidative Stress Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Tyrosine Kinase Activity Regulation Of Phagocytosis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Translation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Regulation Of CAMP Metabolic Process Zymogen Activation Regulation Of Embryonic Development Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Kinase B Signaling Positive Regulation Of Endopeptidase Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Osteoblast Differentiation Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Peptidase Activity Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Growth
Tagcloud ?		aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	associates blots cbl distinct domain element engaged far fusion fyn gamma glutathione hematopoietic interacts jak kinases manner oncogene p59 product proto selectively sh2 stimulation transferase tyk via western
Tagcloud (Difference) ?		aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmed10 tmem70 y2h	associates blots cbl distinct domain element engaged far fusion fyn gamma glutathione hematopoietic interacts jak kinases manner oncogene p59 product proto selectively sh2 stimulation transferase tyk via western
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