KATNB1 and PAFAH1B1

Number of citations of the paper that reports this interaction (PMID 16203747)
30

Data Source:
BioGRID (pull down, affinity chromatography technology)

		KATNB1	PAFAH1B1
Gene Name		katanin p80 (WD repeat containing) subunit B 1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Microtubule Plasma Membrane Katanin Complex Microtubule Cytoskeleton Membrane Axon Growth Cone Midbody Neuronal Cell Body	Astral Microtubule Kinetochore Nuclear Envelope Centrosome Cytosol Kinesin Complex Microtubule Associated Complex Cell Cortex Axon Growth Cone Cell Leading Edge Motile Primary Cilium Nuclear Membrane Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Microtubule Binding Microtubule-severing ATPase Activity Dynein Binding Protein Heterodimerization Activity	Protein Binding Microtubule Binding Heparin Binding Dynactin Binding Protein Homodimerization Activity Phospholipase Binding Dynein Binding Dynein Intermediate Chain Binding Phosphoprotein Binding
	Biological Process	Protein Targeting Negative Regulation Of Microtubule Depolymerization Mitotic Chromosome Movement Towards Spindle Pole Metabolic Process Positive Regulation Of Cell Death Positive Regulation Of Neuron Projection Development Positive Regulation Of Microtubule Depolymerization Microtubule Severing Cell Division	G2/M Transition Of Mitotic Cell Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Mitotic Cell Cycle Ameboidal-type Cell Migration Acrosome Assembly Neuron Migration Positive Regulation Of Cytokine-mediated Signaling Pathway Organelle Organization Microtubule-based Process Mitotic Nuclear Division Nuclear Migration Synaptic Transmission Neuroblast Proliferation Learning Or Memory Retrograde Axon Cargo Transport Adult Locomotory Behavior Protein Secretion Negative Regulation Of Neuron Projection Development Lipid Catabolic Process Stem Cell Division Transmission Of Nerve Impulse Corpus Callosum Morphogenesis Hippocampus Development Layer Formation In Cerebral Cortex Cerebral Cortex Neuron Differentiation Cerebral Cortex Development Actin Cytoskeleton Organization Microtubule Organizing Center Organization Regulation Of Rho GTPase Activity Osteoclast Development Positive Regulation Of Axon Extension Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of JNK Cascade Platelet Activating Factor Metabolic Process Vesicle Transport Along Microtubule Brain Morphogenesis Neuromuscular Process Controlling Balance Nuclear Envelope Disassembly Establishment Of Centrosome Localization
Pathways			Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: DYNC1H1 KATNA1 PAFAH1B1 TGFBR1 XRN1	22 interactors: CLIP1 CSNK2A1 DAB1 DCTN1 DCTN2 DCX DISC1 DNAI1 HSPH1 KARS KATNA1 KATNB1 MAP1B MAP2 NDE1 NDEL1 NUDC PAFAH1B2 PAFAH1B3 PDE4D TNIK TUBA1A
Entrez ID		10300	5048
HPRD ID		04081	03329
Ensembl ID		ENSG00000140854	ENSG00000007168
Uniprot IDs		Q9BVA0	P43034
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Cell Cycle Microtubule Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Cell Projection Organization Mitotic Cell Cycle Process Negative Regulation Of Neuron Projection Development Positive Regulation Of Cell Growth G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Differentiation Mitotic Cell Cycle Microtubule-based Process Negative Regulation Of Cell Projection Organization Cell Migration Regulation Of Cell Development Neuron Migration Cell Motility Ameboidal-type Cell Migration Establishment Of Centrosome Localization Negative Regulation Of Neuron Differentiation Positive Regulation Of Growth Platelet Activating Factor Metabolic Process Cytoskeleton Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Projection Organization Nuclear MRNA Surveillance Locomotion Negative Regulation Of Neurogenesis Corpus Callosum Morphogenesis Microtubule-based Movement Mitotic Nuclear Division Parathyroid Gland Development Osteoclast Development RNA Surveillance Negative Regulation Of Cell Development Histone MRNA Catabolic Process Regulation Of Cell Growth Cytoplasmic MRNA Processing Body Assembly Retrograde Axon Cargo Transport Microtubule Severing RRNA Catabolic Process Endothelial Cell Activation Regulation Of Neuron Projection Development Generation Of Neurons Regulation Of Cell Differentiation Nuclear Migration Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus Neurogenesis	Microtubule-based Process Microtubule Cytoskeleton Organization Mitotic Cell Cycle Process Mitotic Nuclear Division Mitotic Cell Cycle Nervous System Development Neuron Migration Cell Cycle Process Movement Of Cell Or Subcellular Component Cytoskeleton Organization Regulation Of Neuron Projection Development Generation Of Neurons Organelle Localization Neurogenesis Microtubule Bundle Formation Cytoskeleton-dependent Intracellular Transport Cell Cycle Multicellular Organismal Development Regulation Of Cell Projection Organization System Development Establishment Of Organelle Localization Regulation Of Neuron Differentiation Organelle Organization Developmental Process Central Nervous System Development Anatomical Structure Development Regulation Of Neurogenesis Cellular Localization Brain Development G2/M Transition Of Mitotic Cell Cycle Microtubule-based Transport Cell Projection Organization Head Development Cell Migration Microtubule-based Movement Regulation Of Cell Development Dendrite Development Locomotion Establishment Of Chromosome Localization Cell Motility Cell Differentiation Cerebral Cortex Development Organelle Transport Along Microtubule Neuron Projection Extension Cerebral Cortex Radially Oriented Cell Migration Regulation Of Cellular Component Organization Positive Regulation Of Neurogenesis Establishment Of Vesicle Localization Mitotic Centrosome Separation Microtubule Severing
Tagcloud ?			acetylhydrolase alleles autonomous bulb cerebellar defects delayed developmental die disorganization display dosage embryogenesis heterozygous hippocampal homozygous implantation inactive lis1 lissencephaly migration neuronal null olfactory participates phenotypes soon thought understand
Tagcloud (Difference) ?			acetylhydrolase alleles autonomous bulb cerebellar defects delayed developmental die disorganization display dosage embryogenesis heterozygous hippocampal homozygous implantation inactive lis1 lissencephaly migration neuronal null olfactory participates phenotypes soon thought understand
Tagcloud (Intersection) ?