PAFAH1B1 and DNAI1

Number of citations of the paper that reports this interaction (PMID 11889140)
75

Data Source:
HPRD (in vivo)

		PAFAH1B1	DNAI1
Gene Name		platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	dynein, axonemal, intermediate chain 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Astral Microtubule Kinetochore Nuclear Envelope Centrosome Cytosol Kinesin Complex Microtubule Associated Complex Cell Cortex Axon Growth Cone Cell Leading Edge Motile Primary Cilium Nuclear Membrane Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cytoplasm Cytoskeleton Microtubule Cilium Dynein Complex
	Molecular Function	Protein Binding Microtubule Binding Heparin Binding Dynactin Binding Protein Homodimerization Activity Phospholipase Binding Dynein Binding Dynein Intermediate Chain Binding Phosphoprotein Binding	Motor Activity Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Establishment Of Mitotic Spindle Orientation Microtubule Cytoskeleton Organization Mitotic Cell Cycle Ameboidal-type Cell Migration Acrosome Assembly Neuron Migration Positive Regulation Of Cytokine-mediated Signaling Pathway Organelle Organization Microtubule-based Process Mitotic Nuclear Division Nuclear Migration Synaptic Transmission Neuroblast Proliferation Learning Or Memory Retrograde Axon Cargo Transport Adult Locomotory Behavior Protein Secretion Negative Regulation Of Neuron Projection Development Lipid Catabolic Process Stem Cell Division Transmission Of Nerve Impulse Corpus Callosum Morphogenesis Hippocampus Development Layer Formation In Cerebral Cortex Cerebral Cortex Neuron Differentiation Cerebral Cortex Development Actin Cytoskeleton Organization Microtubule Organizing Center Organization Regulation Of Rho GTPase Activity Osteoclast Development Positive Regulation Of Axon Extension Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of JNK Cascade Platelet Activating Factor Metabolic Process Vesicle Transport Along Microtubule Brain Morphogenesis Neuromuscular Process Controlling Balance Nuclear Envelope Disassembly Establishment Of Centrosome Localization	Metabolic Process Cell Projection Organization
Pathways		Mitotic Prometaphase Organelle biogenesis and maintenance Separation of Sister Chromatids Assembly of the primary cilium G2/M Transition Mitotic Anaphase Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane M Phase Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: CLIP1 CSNK2A1 DAB1 DCTN1 DCTN2 DCX DISC1 DNAI1 HSPH1 KARS KATNA1 KATNB1 MAP1B MAP2 NDE1 NDEL1 NUDC PAFAH1B2 PAFAH1B3 PDE4D TNIK TUBA1A	1 interactors: PAFAH1B1
Entrez ID		5048	27019
HPRD ID		03329	05080
Ensembl ID		ENSG00000007168	ENSG00000122735
Uniprot IDs		P43034	Q9UI46
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Microtubule Cytoskeleton Organization Mitotic Cell Cycle Process Mitotic Nuclear Division Mitotic Cell Cycle Nervous System Development Neuron Migration Cell Cycle Process Movement Of Cell Or Subcellular Component Cytoskeleton Organization Regulation Of Neuron Projection Development Generation Of Neurons Organelle Localization Neurogenesis Microtubule Bundle Formation Cytoskeleton-dependent Intracellular Transport Cell Cycle Multicellular Organismal Development Regulation Of Cell Projection Organization System Development Establishment Of Organelle Localization Regulation Of Neuron Differentiation Organelle Organization Developmental Process Central Nervous System Development Anatomical Structure Development Regulation Of Neurogenesis Cellular Localization Brain Development G2/M Transition Of Mitotic Cell Cycle Microtubule-based Transport Cell Projection Organization Head Development Cell Migration Microtubule-based Movement Regulation Of Cell Development Dendrite Development Locomotion Establishment Of Chromosome Localization Cell Motility Cell Differentiation Cerebral Cortex Development Organelle Transport Along Microtubule Neuron Projection Extension Cerebral Cortex Radially Oriented Cell Migration Regulation Of Cellular Component Organization Positive Regulation Of Neurogenesis Establishment Of Vesicle Localization Mitotic Centrosome Separation Microtubule Severing	Establishment Of Centrosome Localization Platelet Activating Factor Metabolic Process Corpus Callosum Morphogenesis Osteoclast Development Retrograde Axon Cargo Transport Nuclear Migration Acrosome Assembly Corpus Callosum Development Establishment Of Nucleus Localization Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Centrosome Localization Negative Regulation Of JNK Cascade Cerebral Cortex Neuron Differentiation Vesicle Transport Along Microtubule Negative Regulation Of Stress-activated MAPK Cascade Secretory Granule Organization Establishment Of Mitotic Spindle Orientation Positive Regulation Of Axon Extension Layer Formation In Cerebral Cortex Central Nervous System Projection Neuron Axonogenesis Nuclear Envelope Disassembly Brain Morphogenesis Stem Cell Division Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Osteoclast Differentiation Nucleus Localization Cerebral Cortex Radial Glia Guided Migration Axon Cargo Transport Spindle Localization Organelle Transport Along Microtubule Neuroblast Proliferation Transmission Of Nerve Impulse Cerebral Cortex Radially Oriented Cell Migration Glial Cell Migration Central Nervous System Neuron Axonogenesis Nuclear Envelope Organization Regulation Of Axon Extension Hippocampus Development Positive Regulation Of Axonogenesis Neuromuscular Process Controlling Balance Stem Cell Proliferation Cerebral Cortex Cell Migration Regulation Of Cytokine-mediated Signaling Pathway Limbic System Development Telencephalon Cell Migration Forebrain Cell Migration Central Nervous System Neuron Development Neural Precursor Cell Proliferation
Tagcloud ?		acetylhydrolase alleles autonomous bulb cerebellar defects delayed developmental die disorganization display dosage embryogenesis heterozygous hippocampal homozygous implantation inactive lis1 lissencephaly migration neuronal null olfactory participates phenotypes soon thought understand
Tagcloud (Difference) ?		acetylhydrolase alleles autonomous bulb cerebellar defects delayed developmental die disorganization display dosage embryogenesis heterozygous hippocampal homozygous implantation inactive lis1 lissencephaly migration neuronal null olfactory participates phenotypes soon thought understand
Tagcloud (Intersection) ?