SPRY1 and KRTAP10-1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPRY1	KRTAP10-1
Gene Name		sprouty homolog 1, antagonist of FGF signaling (Drosophila)	keratin associated protein 10-1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane	Keratin Filament
	Molecular Function	Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Metanephros Development Ureteric Bud Development Organ Induction Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		Signaling by EGFR EGFR downregulation Signaling by EGFR in Cancer Signaling by Ligand-Responsive EGFR Variants in Cancer Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by EGFRvIII in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ATXN7 CACNA1A CREB5 GEMIN4 GRB2 HEXIM2 HOXA1 HRG KPNA2 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 LCE1B LCE2D MDFI MEOX2 NOTCH2NL OTX1 R3HDM2 SOCS4 SPRY2 STAT3 YY1	73 interactors: ADAMTSL4 AEN AVPI1 BAHD1 BCL6B C19orf66 CARD9 CATSPER1 CBX2 CHIC2 CHRD CREB5 CXCL16 DAAM2 DHX57 DKK1 DOCK2 ECE1 FAM76B GLRX3 HOXA1 HPCAL1 HSD3B7 KRTAP10-3 KRTAP12-1 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E MAPKBP1 MEOX2 MOBP NOTCH2NL NPDC1 NR4A1 OTX1 PID1 PIN1 POM121L8P PRM2 PRPF31 PVRL2 RSPO2 SLC23A1 SLC6A20 SPATA8 SPRY1 SPRY2 TULP3 ZBTB24 ZNF101 ZNF124 ZNF264 ZNF286A ZNF329 ZNF417 ZNF433 ZNF439 ZNF440 ZNF559 ZNF572 ZNF581 ZNF587 ZNF785 ZSCAN12 ZSCAN26
Entrez ID		10252	386677
HPRD ID		06782	11184
Ensembl ID		ENSG00000164056	ENSG00000215455
Uniprot IDs		O43609	P60331
PDB IDs
Enriched GO Terms of Interacting Partners?		Organ Development Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development System Development Developmental Process Anatomical Structure Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Negative Regulation Of ERBB Signaling Pathway Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Pattern Specification Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Embryonic Organ Development Regulation Of ERBB Signaling Pathway Regulation Of Phosphorylation Pons Development Anterior/posterior Pattern Specification Inner Ear Morphogenesis Sensory Organ Development Regulation Of Phosphorus Metabolic Process Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Morphogenesis Embryonic Morphogenesis Ear Morphogenesis Negative Regulation Of Signal Transduction Metencephalon Development Embryo Development Transcription, DNA-templated Negative Regulation Of Signaling Negative Regulation Of Phosphorylation RNA Biosynthetic Process Hindbrain Development RNA Metabolic Process Regulation Of Gene Expression Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Inner Ear Development Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Keratinization Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Biosynthetic Process Lung Growth Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Regulation Of Neurotrophin TRK Receptor Signaling Pathway Limb Development Embryonic Morphogenesis Pattern Specification Process Developmental Process Embryonic Neurocranium Morphogenesis Epithelial Tube Branching Involved In Lung Morphogenesis Epithelium Development Cellular Process Bud Elongation Involved In Lung Branching Negative Regulation Of ERK1 And ERK2 Cascade Multicellular Organismal Development Respiratory Tube Development Anterior/posterior Pattern Specification Organ Development Lung Morphogenesis Respiratory System Development Embryonic Limb Morphogenesis Tissue Development Cell Differentiation Negative Regulation Of Ras GTPase Activity Limb Morphogenesis Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Tube Development Embryo Development Branch Elongation Of An Epithelium Inner Ear Morphogenesis
Tagcloud ?		adaptors coimmunoprecipitated comprises dok1 epcs epo epor erythroblast erythroblasts gab1 hemoglobinizing homo irs2 orf phosphoproteomics phosphotyrosine primates propagates py rhex sapiens sh2d2a shc1 sprouty spry2 stam2 transducing ut7epo validating
Tagcloud (Difference) ?		adaptors coimmunoprecipitated comprises dok1 epcs epo epor erythroblast erythroblasts gab1 hemoglobinizing homo irs2 orf phosphoproteomics phosphotyrosine primates propagates py rhex sapiens sh2d2a shc1 sprouty spry2 stam2 transducing ut7epo validating
Tagcloud (Intersection) ?