SLC75A1 and NPSR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		SLC75A1	NPSR1
Description		solute carrier family 75 member 1	neuropeptide S receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Organelle Membrane Brush Border Membrane	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding Tetracycline Transmembrane Transporter Activity Organic Anion Transmembrane Transporter Activity Transmembrane Transporter Activity	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Neuropeptide Receptor Activity
	Biological Process	Apoptotic Process Tetracycline Transmembrane Transport Sodium-independent Organic Anion Transport Transmembrane Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Eating Behavior Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Righting Reflex Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Eating Behavior Negative Regulation Of Defecation
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events G alpha (s) signalling events
Drugs			Halothane
Diseases
GWAS			Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Asthma ( 29273806) Leisure-time exercise behaviour ( 30102679) Plasma anti-thyroglobulin levels ( 29678681) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		4 interacting genes: CLK1 F2RL1 NPSR1 SRPK2	16 interacting genes: ATP5F1A CCT2 ENTPD6 GABARAPL2 HLA-C IPO13 PGM2L1 PMPCB PRR36 RABGGTB SLC3A2 SLC41A3 SLC75A1 TERF2IP TMED10 TMEM101
Entrez ID		10227	387129
HPRD ID		10265	10547
Ensembl ID		ENSG00000109736	ENSG00000187258
Uniprot IDs		D6R9N3 D6RA47 D6RE79 Q14728	A0A090N8Z1 Q6W5P4
PDB IDs		6S4M
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Proteinase-activated Receptor Activity Positive Regulation Of Glomerular Filtration Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Negative Regulation Of Secretion Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Eating Behavior Negative Regulation Of Defecation Positive Regulation Of Killing Of Cells Of Another Organism Nuclear Speck Organization Mature Conventional Dendritic Cell Differentiation Thrombin-activated Receptor Activity Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Feeding Behavior Vasopressin Receptor Activity Regulation Of Eating Behavior Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Regulation Of Toll-like Receptor 3 Signaling Pathway Thrombin-activated Receptor Signaling Pathway Positive Regulation Of Defense Response To Bacterium Positive Regulation Of Actin Filament Depolymerization Positive Regulation Of Pseudopodium Assembly G Protein-coupled Receptor Activity Positive Regulation Of Phagocytosis, Engulfment Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Glomerular Filtration R-loop Processing Righting Reflex Negative Regulation Of Transport Regulation Of Defense Response To Bacterium Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Depolymerization Pseudopodium Nuclear Body Organization Reflex Protein Kinase Activity Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Superoxide Anion Generation Cell-cell Junction Maintenance Positive Regulation Of Superoxide Anion Generation	Mitochondrial Processing Peptidase Complex Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Protein Processing Adenyl Ribonucleotide Binding Transmembrane Transport Guanosine-5'-triphosphate,3'-diphosphate Diphosphatase Activity Apical Pole Of Neuron Tetracycline Transmembrane Transport Tetracycline Transmembrane Transporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Glucose-1,6-bisphosphate Synthase Activity
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