USPL1 and RANGAP1

Number of citations of the paper that reports this interaction (PMID 22878415)
10

Data Source:
BioGRID (enzymatic study)

		USPL1	RANGAP1
Gene Name		ubiquitin specific peptidase like 1	Ran GTPase activating protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cajal Body	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nuclear Pore Cytoplasm Cytosol Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding SUMO Binding Ubiquitin Binding SUMO-specific Isopeptidase Activity	Ran GTPase Activator Activity Protein Binding
	Biological Process	Proteolysis Cell Proliferation Protein Desumoylation Cajal Body Organization	Mitotic Cell Cycle Signal Transduction Positive Regulation Of Ran GTPase Activity Negative Regulation Of Protein Export From Nucleus
Pathways			Mitotic Prometaphase Separation of Sister Chromatids HIV Infection Host Interactions of HIV factors Rev-mediated nuclear export of HIV RNA Mitotic Anaphase Interactions of Rev with host cellular proteins M Phase Cell Cycle, Mitotic Late Phase of HIV Life Cycle HIV Life Cycle Rev-mediated nuclear export of HIV RNA Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: RANGAP1 SP100 SUMO1 SUMO2 SUMO3	14 interactors: CCL5 CSNK2A1 GNAI1 GNAI3 IPO8 RAN RANBP2 SENP1 SENP2 SUMO1 SUMO2 SUMO3 UBE2I USPL1
Entrez ID		10208	5905
HPRD ID		09833	03839
Ensembl ID		ENSG00000132952	ENSG00000100401
Uniprot IDs		A8K1B1 Q5W0Q7	F8W7I9 P46060 Q9BSK3
PDB IDs			1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2IO2 2IO3 2IY0 3UIN 3UIO 3UIP
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Negative Regulation Of Protein Export From Nucleus Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Post-translational Protein Modification Positive Regulation Of Protein Catabolic Process Peptidyl-lysine Modification Regulation Of Protein Export From Nucleus Positive Regulation Of Proteolysis Negative Regulation Of DNA Binding Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of DNA Binding Negative Regulation Of Intracellular Protein Transport Protein Modification By Small Protein Conjugation Negative Regulation Of Binding Regulation Of Proteolysis Negative Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Cellular Response To Interferon-gamma Regulation Of Fas Signaling Pathway Response To Interferon-gamma Protein Localization To Nucleus Negative Regulation Of Protein Transport Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Nucleocytoplasmic Transport PML Body Organization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Binding Protein Localization To Nuclear Pore Positive Regulation Of Ran GTPase Activity Regulation Of Intracellular Protein Transport Positive Regulation Of Protein Metabolic Process Protein Localization To Nuclear Envelope Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Transport DNA Damage Response, Signal Transduction Resulting In Transcription Regulation Of Metabolic Process Regulation Of Intracellular Transport Cytokine-mediated Signaling Pathway Protein Localization To Organelle Regulation Of Interferon-gamma-mediated Signaling Pathway	Protein Sumoylation Peptidyl-lysine Modification Protein Desumoylation Post-translational Protein Modification Peptidyl-amino Acid Modification Protein Modification By Small Protein Conjugation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Protein Localization To Nucleus Positive Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Proteolysis Protein Modification By Small Protein Removal Nucleus Organization Regulation Of Cellular Protein Metabolic Process Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Cell Division Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Protein Metabolic Process Signal Transduction Protein Localization To Organelle Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Binding Vesicle Fusion Protein Localization Metabolic Process Mitotic Cell Cycle Process Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Localization Mitotic Cell Cycle Positive Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Negative Regulation Of Cellular Protein Catabolic Process
Tagcloud ?			apl bodies compartmentalisation covalently dependant disrupted fits indirectly kr leukaemia localisation localises lys487 lys490 modification modifies mutagenesis named nd10 phosphoprotein pic1 pml pods promyelocytic rara subcellular sumo translocated ubc9
Tagcloud (Difference) ?			apl bodies compartmentalisation covalently dependant disrupted fits indirectly kr leukaemia localisation localises lys487 lys490 modification modifies mutagenesis named nd10 phosphoprotein pic1 pml pods promyelocytic rara subcellular sumo translocated ubc9
Tagcloud (Intersection) ?