USPL1

Description		ubiquitin specific peptidase like 1
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GO Annotations	Cellular Component	Extracellular Space Nucleus Cajal Body
	Molecular Function	Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity DeSUMOylase Activity SUMO Binding Ubiquitin Binding
	Biological Process	Proteolysis Cell Population Proliferation SnRNA Transcription Protein Desumoylation Cajal Body Organization
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		6 interacting genes: RANGAP1 SP100 SUMO1 SUMO2 SUMO3 TSC2
Entrez ID		10208
HPRD ID		09833
Ensembl ID		ENSG00000132952
Uniprot IDs		A8K1B1 B3KQ64 Q5W0Q7
PDB IDs		7P99 7ZJU 7ZJV
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Protein Tag Activity PML Body Ubiquitin-like Protein Ligase Binding Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Intracellular Transport Negative Regulation Of Protein Export From Nucleus Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Protein Transport Negative Regulation Of Establishment Of Protein Localization Regulation Of Intracellular Protein Transport Negative Regulation Of DNA Binding Maintenance Of Protein Location In Nucleus Protein Modification By Small Protein Conjugation Negative Regulation Of Protein Localization Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Protein Export From Nucleus Regulation Of Intracellular Transport Post-translational Protein Modification Maintenance Of Protein Localization In Organelle Ubiquitin Protein Ligase Binding Regulation Of Protein Localization Regulation Of DNA Binding Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Negative Regulation Of Transport Regulation Of Protein Transport Maintenance Of Location Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nuclear Pore Macromolecule Metabolic Process Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Cytoplasmic Periphery Of The Nuclear Pore Complex Protein Metabolic Process Regulation Of Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Modification Process TSC1-TSC2 Complex Protein Localization To Nuclear Pore Regulation Of Protein Localization To Nucleus SUMO Ligase Complex Nuclear Pore Cytoplasmic Filaments Kinetochore
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