PAX4 and NAIF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PAX4	NAIF1
Description		paired box 4	nuclear apoptosis inducing factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm Mitochondrion Cytosol Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Type B Pancreatic Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Brain Development Sensory Organ Development Animal Organ Morphogenesis Cell Differentiation Forebrain Development Animal Organ Development Retina Development In Camera-type Eye	Apoptotic Process Negative Regulation Of Cell Growth Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Pathways
Drugs
Diseases		Maturity onset diabetes of the young (MODY)
GWAS		Fruit consumption ( 32066663) Left-handedness ( 32989287) Metabolite levels ( 23823483) Nonsyndromic cleft palate ( 31609978) Type 2 diabetes ( 22158537 23532257 26818947 29632382 30718926 32499647 32794382) Type 2 diabetes (adjusted for BMI) ( 29632382)	Albumin-globulin ratio ( 29403010) Body mass index ( 26426971) Monocyte count ( 29403010)
Interacting Genes		14 interacting genes: AURKA CABP5 EIF4A3 FBXO2 GMCL1 NAIF1 NECAB1 NFYC NME7 NRXN3 NTM NUTF2 PSMC1 UBL5	5 interacting genes: CCNDBP1 PAX4 SOX14 TERF2 TERF2IP
Entrez ID		5078	203245
HPRD ID		01333	12987
Ensembl ID		ENSG00000106331	ENSG00000171169
Uniprot IDs		A0A1W2PPX4 J3KPG0	Q69YI7
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of DNA Recombination At Telomere Shelterin Complex Protection From Non-homologous End Joining At Telomere Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Telomere Capping Telomere Maintenance In Response To DNA Damage RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Negative Regulation Of DNA Recombination Male Germ Cell Nucleus Nuclear Body Positive Regulation Of Telomere Maintenance Telomere Cap Complex DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Recombination Negative Regulation Of Chromosome Organization Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair Telomere Maintenance Positive Regulation Of Chromosome Organization Protein Localization To Chromosome Regulation Of Telomere Maintenance Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Telomere Organization Negative Regulation Of DNA Metabolic Process Regulation Of DNA Recombination Negative Regulation Of T-circle Formation Chromosome, Telomeric Region Negative Regulation Of Mitotic Recombination Regulation Of DNA Repair Brain Development Telomerase Activity Regulation Of Mitotic Recombination Regulation Of Chromosome Organization Negative Regulation Of Telomere Capping Type B Pancreatic Cell Differentiation Positive Regulation Of DNA Metabolic Process Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Telomeric Loop Disassembly Chromosome Organization Regulation Of Telomere Capping Enteroendocrine Cell Differentiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?