CKMT1B and VDAC1

Number of citations of the paper that reports this interaction (PMID 11602586)
17

Data Source:
HPRD (in vitro)

		CKMT1B	VDAC1
Gene Name		creatine kinase, mitochondrial 1B	voltage-dependent anion channel 1
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Extracellular Vesicular Exosome	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Plasma Membrane Membrane Mitochondrial Nucleoid Pore Complex Extracellular Vesicular Exosome
	Molecular Function	Creatine Kinase Activity ATP Binding	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding
	Biological Process	Creatine Metabolic Process Phosphorylation Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process	Behavioral Fear Response Anion Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Viral Process Epithelial Cell Differentiation Regulation Of Anion Transport Transmembrane Transport
Pathways		Metabolism of amino acids and derivatives Creatine metabolism	Mitochondrial protein import
Drugs		Creatine
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CALM1 SLC25A5 VDAC1	20 interactors: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE RAF1 SUMO4 TOMM20 TUBA4A
Entrez ID		1159	7416
HPRD ID		00424	05137
Ensembl ID		ENSG00000237289	ENSG00000213585
Uniprot IDs		P12532	B3KTS5 P21796
PDB IDs		1QK1	2JK4 2K4T
Enriched GO Terms of Interacting Partners?		Energy Reserve Metabolic Process Adenine Transport Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of High Voltage-gated Calcium Channel Activity Purine Nucleobase Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Nucleobase Transport Negative Regulation Of Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Generation Of Precursor Metabolites And Energy Regulation Of Ion Transmembrane Transport Regulation Of Intracellular Transport Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Viral Process Positive Regulation Of Phosphoprotein Phosphatase Activity Synaptic Transmission Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Regulation Of Ion Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Negative Regulation Of Mitochondrion Organization Positive Regulation Of Cation Channel Activity Response To Amphetamine Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Apoptotic Mitochondrial Changes Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Extrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Mitochondrial Transport Positive Regulation Of Release Of Cytochrome C From Mitochondria Thymocyte Apoptotic Process B Cell Apoptotic Process Post-embryonic Organ Morphogenesis Positive Regulation Of Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Mitochondrion Organization Mitochondrion Organization Positive Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Mitochondrion Organization Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway T Cell Apoptotic Process Apoptotic Signaling Pathway Transport Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization B Cell Negative Selection Apoptotic Process Involved In Morphogenesis Organelle Organization Apoptotic Process Involved In Development Establishment Of Localization In Cell Intracellular Transport Release Of Cytochrome C From Mitochondria Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Apoptotic Process Involved In Embryonic Digit Morphogenesis Post-embryonic Camera-type Eye Morphogenesis Positive Regulation Of Intracellular Signal Transduction Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction B Cell Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Developmental Programmed Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Apoptotic Process
Tagcloud ?			000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle
Tagcloud (Difference) ?			000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle
Tagcloud (Intersection) ?