CKMT1B and SLC25A5

Number of citations of the paper that reports this interaction (PubMedID 11602586)
0

Data Source:
HPRD (in vivo)

		CKMT1B	SLC25A5
Description		creatine kinase, mitochondrial 1B	solute carrier family 25 member 5
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Membrane Mitochondrial Nucleoid MMXD Complex
	Molecular Function	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups	Adenine Nucleotide Transmembrane Transporter Activity RNA Binding ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Antiporter Activity Oxidative Phosphorylation Uncoupler Activity Ubiquitin Protein Ligase Binding
	Biological Process	Phosphocreatine Biosynthetic Process	Chromosome Segregation Positive Regulation Of Cell Population Proliferation Adenine Transport B Cell Differentiation Erythrocyte Differentiation Regulation Of Mitochondrial Membrane Permeability Adenine Nucleotide Transport Transmembrane Transport Mitochondrial ADP Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor Adaptive Thermogenesis
Pathways		Creatine metabolism	Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Mitochondrial protein degradation
Drugs		Creatine Phosphocreatine	Clodronic acid Etidronic acid
Diseases
GWAS
Interacting Genes		12 interacting genes: ASB9 CALM1 CTNNA3 HPCA NUTF2 OCM PPP1R16A PSMC3 RXRG SFRP4 SLC25A5 VDAC1	6 interacting genes: CEBPA CKMT1B DUX4 NFKBIA PTEN RNF26
Entrez ID		1159	292
HPRD ID		00424	02147
Ensembl ID		ENSG00000237289	ENSG00000005022
Uniprot IDs		P12532	P05141 Q6NVC0
PDB IDs		1QK1 9B04 9B05 9B0T 9B0U 9B14 9B16
Enriched GO Terms of Interacting Partners?		Mitochondrial Permeability Transition Pore Complex Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Catabolic Process Mitochondrial Nucleoid Regulation Of Mitophagy Negative Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Action Potential Regulation Of Monoatomic Cation Transmembrane Transport Negative Regulation Of Sodium-dependent Phosphate Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Transmembrane Transporter Activity Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Contraction Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Receptor Internalization Response To Ketamine Adenine Nucleotide Transmembrane Transporter Activity Mitochondrial ADP Transmembrane Transport ATP:ADP Antiporter Activity MMXD Complex Positive Regulation Of Macroautophagy Regulation Of Transport Adenine Transmembrane Transporter Activity Oxidative Phosphorylation Uncoupler Activity Adenine Transport Transmembrane Transporter Binding Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Transport Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Response To Calcium Ion Negative Regulation Of Monoatomic Ion Transport Regulation Of Heart Rate Negative Regulation Of Transmembrane Transport Regulation Of Monoatomic Ion Transport Regulation Of Striated Muscle Contraction Response To Aroclor 1254 Regulation Of Receptor-mediated Endocytosis Dendritic Spine Head	Notch Signaling Pathway Regulation Of Osteoblast Differentiation Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Positive Regulation Of RNA Biosynthetic Process Response To Tumor Necrosis Factor Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Cell Population Proliferation Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Cell Differentiation Positive Regulation Of DNA-templated Transcription Cellular Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Vitamin B2 C/EBP Complex Positive Regulation Of Transcription By RNA Polymerase II I-kappaB/NF-kappaB Complex Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Proteolysis Negative Regulation Of Cell Population Proliferation Regulation Of Defense Response Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Development White Fat Cell Proliferation Positive Regulation Of RNA Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Inflammatory Response Rb-E2F Complex Phosphocreatine Biosynthetic Process Creatine Kinase Activity Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Developmental Maturation Intracellular Signaling Cassette Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Phenylpropanoid Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly
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