PRR13 and GPAA1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PRR13	GPAA1
Gene Name		proline rich 13	glycosylphosphatidylinositol anchor attachment 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function		GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Protein Complex Assembly C-terminal Protein Lipidation Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Post-translational protein modification Attachment of GPI anchor to uPAR Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: BAIAP2 EWSR1 FAM133A GPAA1 KLHL12 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP4-12 LGALS3 LNX1 PEX5 PLSCR1 PPIA PSMA3 PSME3 RP9P RTN4 SDCBP SDCBP2 SRI TNFAIP8 VAC14 ZCCHC10	7 interactors: EIF3E GRIK5 PIGK PIGT PIGU PIN1 PRR13
Entrez ID		54458	8733
HPRD ID		13211	04334
Ensembl ID		ENSG00000205352	ENSG00000197858
Uniprot IDs		F8VRX0 Q9NZ81	O43292
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Canonical Wnt Signaling Pathway Endomembrane System Organization Cell Migration Membrane Organization Cell Motility Negative Regulation Of Wnt Signaling Pathway Glycerophospholipid Biosynthetic Process Endoplasmic Reticulum Organization Apoptotic Process Response To Stimulus Viral Process Regulation Of Canonical Wnt Signaling Pathway Programmed Cell Death Phospholipid Biosynthetic Process Regulation Of Signaling Protein Ubiquitination Cell Death Death Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Protein Modification By Small Protein Conjugation Negative Regulation Of Immunological Synapse Formation Uncoating Of Virus Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cellular Localization Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cellular Process Regulation Of Viral Genome Replication Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Glycerophospholipid Metabolic Process Regulation Of Wnt Signaling Pathway Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity Cellular Component Assembly Locomotion Positive Regulation Of Secretion Negative Regulation Of Protein Homotetramerization Intracellular Sequestering Of Iron Ion Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Attachment Of GPI Anchor To Protein C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Macromolecule Biosynthetic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Protein Retention In ER Lumen Cellular Protein Metabolic Process Maintenance Of Protein Localization In Endoplasmic Reticulum Lipid Metabolic Process Biosynthetic Process Negative Regulation Of Translational Initiation Formation Of Translation Preinitiation Complex Cellular Protein Modification Process
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