ZFP42

Description		ZFP42 zinc finger protein
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm PcG Protein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Male Gonad Development Female Gonad Development Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Cortisol levels (saliva) ( 28843169) LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429) Testicular germ cell tumor ( 28604728 28604732) Visceral fat ( 30942860)
Interacting Genes		8 interacting genes: EED LHX2 MEOX2 PIAS2 RNF4 RYBP SUMO1 YAF2
Entrez ID		132625
HPRD ID		15726
Ensembl ID		ENSG00000179059
Uniprot IDs		Q96MM3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II PML Body Transcription Coregulator Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process DNA Binding Regulation Of Macromolecule Metabolic Process Nucleosome Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Transcription Corepressor Activity Negative Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Sumoylation Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Nucleus Negative Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Roof Of Mouth Development Positive Regulation Of Macromolecule Metabolic Process Nuclear Speck Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Adaxial/abaxial Pattern Formation Positive Regulation Of Metabolic Process Regulation Of Kinetochore Assembly Protein Localization To Nuclear Pore Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Somite Specification SUMO Polymer Binding Negative Regulation Of Action Potential Small Protein Activating Enzyme Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Centromere Complex Assembly Nucleoplasm Negative Regulation Of Protein Localization To Chromatin Microtubule End Regulation Of Ubiquitin-dependent Protein Catabolic Process Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Telencephalon Regionalization
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