LRPPRC and HEBP2

Number of citations of the paper that reports this interaction (PMID 11827465)
25

Data Source:
HPRD (two hybrid)

		LRPPRC	HEBP2
Gene Name		leucine-rich pentatricopeptide repeat containing	heme binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Nuclear Chromosome Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Mitochondrion Cytoskeleton Microtubule Membrane Ribonucleoprotein Complex Mitochondrial Nucleoid Perinuclear Region Of Cytoplasm	Cytoplasm Mitochondrion Extracellular Vesicular Exosome
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding Microtubule Binding Poly(A) RNA Binding Beta-tubulin Binding Actin Filament Binding	Protein Binding
	Biological Process	Negative Regulation Of Mitochondrial RNA Catabolic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Mitochondrion Transport Along Microtubule MRNA Transport Regulation Of Mitochondrial Translation	Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Necrotic Cell Death Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Response To Reactive Oxygen Species
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CECR2 FOXO1 HEBP2 MAP1S NFKBIB PPARGC1A UXT	2 interactors: LRPPRC PDCD6
Entrez ID		10128	23593
HPRD ID		06343	09316
Ensembl ID		ENSG00000138095
Uniprot IDs		E5KNY5 P42704	Q9Y5Z4
PDB IDs			3R85 3R8J 3R8K 4AYZ 4B0Y
Enriched GO Terms of Interacting Partners?		Regulation Of Energy Homeostasis Mitochondrion Transport Along Microtubule Establishment Of Mitochondrion Localization Positive Regulation Of Gluconeogenesis Apoptotic DNA Fragmentation Cellular Response To Reactive Nitrogen Species Temperature Homeostasis Apoptotic Nuclear Changes Positive Regulation Of Glucose Metabolic Process Mitochondrion Localization Regulation Of Gluconeogenesis Organelle Transport Along Microtubule Response To Cold Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Cellular Glucose Homeostasis Cellular Response To Nitrite DNA Catabolic Process, Endonucleolytic Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Glucose Metabolic Process Cellular Response To Oxygen Levels Cellular Nitrogen Compound Metabolic Process Fat Cell Differentiation Positive Regulation Of ATP Biosynthetic Process Positive Regulation Of Mitochondrial DNA Metabolic Process Microtubule-based Transport Organelle Organization Cytoskeleton-dependent Intracellular Transport DNA Catabolic Process Cellular Response To Inorganic Substance Regulation Of Carbohydrate Metabolic Process Response To Statin Positive Regulation Of Energy Homeostasis Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Respiration Response To Starvation Response To Temperature Stimulus Negative Regulation Of Mitochondrial Membrane Potential Cellular Response To Oxidative Stress Transcription From RNA Polymerase II Promoter Glucose Homeostasis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Flavone Metabolic Process Response To Norepinephrine Cellular Response To Cold Response To Leucine Multicellular Organismal Homeostasis Apoptotic Process	Negative Regulation Of Mitochondrial RNA Catabolic Process Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Regulation Of Mitochondrial Translation Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Mitochondrion Transport Along Microtubule Establishment Of Mitochondrion Localization Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Mitochondrion Localization Negative Regulation Of Protein Kinase B Signaling Intracellular Transport Organelle Transport Along Microtubule Positive Regulation Of Endothelial Cell Migration Regulation Of TOR Signaling Positive Regulation Of Endothelial Cell Proliferation Cellular Response To Heat Positive Regulation Of Epithelial Cell Migration Regulation Of Cellular Protein Metabolic Process Regulation Of Endothelial Cell Proliferation Establishment Of Localization In Cell Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Mitochondrion Organization Activation Of Cysteine-type Endopeptidase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Zymogen Activation Regulation Of Endothelial Cell Migration Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Heat Response To Calcium Ion Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process MRNA Transport Positive Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Kinase B Signaling Cellular Localization Positive Regulation Of Angiogenesis Positive Regulation Of Endopeptidase Activity Microtubule-based Transport RNA Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Epithelial Cell Migration Positive Regulation Of Peptidase Activity RNA Localization Positive Regulation Of Epithelial Cell Proliferation
Tagcloud ?		adenocarcinomas autophagic autophagosomal autophagy biogenesis bridges c19orf5 collaboration collaboratively diethylnitrosamine guangzhou h2ax hepatocelular immunochemical inc map1a map1b map1s microtubules mitochondrion named originally p62 pca periodicals survive vary wildtype wiley
Tagcloud (Difference) ?		adenocarcinomas autophagic autophagosomal autophagy biogenesis bridges c19orf5 collaboration collaboratively diethylnitrosamine guangzhou h2ax hepatocelular immunochemical inc map1a map1b map1s microtubules mitochondrion named originally p62 pca periodicals survive vary wildtype wiley
Tagcloud (Intersection) ?