ACTR1A and DCTN4

Number of citations of the paper that reports this interaction (PMID 10074429)
17

Data Source:
HPRD (in vivo, in vitro)

		ACTR1A	DCTN4
Gene Name		ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	dynactin 4 (p62)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Associated Complex Extracellular Vesicular Exosome	Nucleus Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Dynactin Complex
	Molecular Function	ATP Binding	Protein N-terminus Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Nuclear Migration Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Adaptive Immune System	MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		6 interactors: ACTR10 DCTN1 DCTN4 NUMA1 SPTBN1 SPTBN2	6 interactors: ACTR1A ATP7B CALCOCO2 GOLGA2 MTUS2 PNMA1
Entrez ID		10121	51164
HPRD ID		05507	13126
Ensembl ID		ENSG00000138107	ENSG00000132912
Uniprot IDs		P61163	Q9NSJ5 Q9UJW0
PDB IDs
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Establishment Of Organelle Localization Actin Filament Capping Organelle Localization Negative Regulation Of Actin Filament Depolymerization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Movement Of Cell Or Subcellular Component Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Complex Disassembly Mitotic Cell Cycle Process Negative Regulation Of Protein Complex Assembly Mitotic Cell Cycle Microtubule-based Process Establishment Of Localization In Cell Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cellular Localization Common-partner SMAD Protein Phosphorylation Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition SMAD Protein Import Into Nucleus Microtubule-based Movement Mitotic Nuclear Division Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Cell Cycle Regulation Of Actin Cytoskeleton Organization Nuclear Migration Axon Guidance Vesicle-mediated Transport Regulation Of Actin Filament-based Process Cerebellar Purkinje Cell Layer Morphogenesis Cell Division Membrane Assembly Golgi To Plasma Membrane Protein Transport Regulation Of Cytoskeleton Organization Membrane Biogenesis Establishment Of Nucleus Localization Axonogenesis	Copper Ion Export Sequestering Of Calcium Ion Intracellular Copper Ion Transport Sequestering Of Metal Ion Copper Ion Transmembrane Transport Copper Ion Import Cellular Zinc Ion Homeostasis Zinc Ion Homeostasis Cellular Copper Ion Homeostasis Copper Ion Homeostasis Response To Copper Ion Copper Ion Transport Immune System Process Inflammatory Response To Antigenic Stimulus
Tagcloud ?		backgrounds bbs2 bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131
Tagcloud (Difference) ?		backgrounds bbs2 bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131
Tagcloud (Intersection) ?