ACTR3 and WASF3

Number of citations of the paper that reports this interaction (PMID 10381382)
54

Data Source:
HPRD (in vivo)

		ACTR3	WASF3
Gene Name		ARP3 actin-related protein 3 homolog (yeast)	WAS protein family, member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Podosome Cytosol Actin Filament Arp2/3 Protein Complex Cell-cell Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Hemidesmosome Excitatory Synapse Extracellular Vesicular Exosome	Cytoplasm Cytoskeleton Lamellipodium Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding	Actin Binding
	Biological Process	Movement Of Cell Or Subcellular Component Establishment Or Maintenance Of Cell Polarity Axon Guidance Asymmetric Cell Division Response To Carbohydrate Positive Regulation Of Lamellipodium Assembly Meiotic Chromosome Movement Towards Spindle Pole Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Myosin II Filament Organization Innate Immune Response Response To Antibiotic Ephrin Receptor Signaling Pathway Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Filopodium Assembly Spindle Localization Cilium Morphogenesis	Protein Complex Assembly Cytoskeleton Organization Regulation Of Cell Shape Oligodendrocyte Development Lamellipodium Assembly Actin Filament Polymerization Positive Regulation Of Myelination
Pathways		EPHB-mediated forward signaling Axon guidance EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System	Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACTR2 ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CDH1 CTTN HCLS1 JUND WASF2 WASF3 WASL	5 interactors: ACTB ACTR3 CAMK2D PIK3R1 PIK3R2
Entrez ID		10096	10810
HPRD ID		05024	05458
Ensembl ID		ENSG00000115091	ENSG00000132970
Uniprot IDs		B4DXW1 P61158	Q5T8P4 Q86VQ2 Q9UPY6
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Actin Cytoskeleton Organization Actin Filament-based Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Ephrin Receptor Signaling Pathway Regulation Of Actin Filament-based Process Cytoskeleton Organization Phagocytosis Cell Projection Organization Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Development Regulation Of Cellular Component Organization Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Immune Response-regulating Cell Surface Receptor Signaling Pathway Endocytosis Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Organelle Organization Positive Regulation Of Actin Filament Polymerization Cell Morphogenesis Cell Differentiation Positive Regulation Of Protein Polymerization Immune Response-regulating Signaling Pathway Neuron Projection Development Cell Projection Morphogenesis Actin Nucleation Regulation Of Immune System Process Cell Part Morphogenesis Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Cellular Component Size Positive Regulation Of Protein Complex Assembly Neuron Development Positive Regulation Of Immune Response Neuron Projection Morphogenesis Organelle Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Actin Polymerization Or Depolymerization Neurogenesis	Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Innate Immune Response Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Immune Response Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Immune System Process Phosphatidylinositol 3-kinase Signaling Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Transcription Factor Import Into Nucleus Regulation Of Phosphatidylinositol 3-kinase Activity Locomotion Cell Surface Receptor Signaling Pathway Regulation Of Immune System Process Regulation Of Lipid Kinase Activity Homeostatic Process Blood Coagulation Hemostasis Regulation Of Intracellular Transport Vesicle-mediated Transport Response To Stress Cellular Glucose Homeostasis Cellular Chemical Homeostasis Regulation Of Transcription Factor Import Into Nucleus Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Protein Import Into Nucleus Ephrin Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus NFAT Protein Import Into Nucleus T Cell Receptor Signaling Pathway Cellular Homeostasis Response To Wounding Phosphatidylinositol Biosynthetic Process Phosphatidylinositol-mediated Signaling Antigen Receptor-mediated Signaling Pathway Insulin Receptor Signaling Pathway
Tagcloud ?		actb anxa2 anxa6 canine cope dedifferentiation grade histologically hspa9 interesting kit mast mct mcts mutational noteworthy observable oncology paradox pdia3 proliferating proteome reflected tcp1a tcp1e transferrin tryptase tumours wdr1	activates aspect aspects cooperates cytokines effectors inactivation independently invasion jak leads lethal matrix metalloproteinases metastasis micrornas movement nfkappab opportunities played promote promotes promoting regulating stat3 suppress suppresses upregulate zeb1
Tagcloud (Difference) ?		actb anxa2 anxa6 canine cope dedifferentiation grade histologically hspa9 interesting kit mast mct mcts mutational noteworthy observable oncology paradox pdia3 proliferating proteome reflected tcp1a tcp1e transferrin tryptase tumours wdr1	activates aspect aspects cooperates cytokines effectors inactivation independently invasion jak leads lethal matrix metalloproteinases metastasis micrornas movement nfkappab opportunities played promote promotes promoting regulating stat3 suppress suppresses upregulate zeb1
Tagcloud (Intersection) ?