BLMH and TRIM47

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BLMH	TRIM47
Description		bleomycin hydrolase	tripartite motif containing 47
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleus Cytoplasm Cytosol Postsynapse Glutamatergic Synapse
	Molecular Function	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Identical Protein Binding Cysteine-type Aminopeptidase Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Proteolysis Response To Xenobiotic Stimulus Response To Toxic Substance Homocysteine Catabolic Process	Protein Ubiquitination Regulation Of Postsynapse Assembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Periventricular white matter hyperintensities ( 32517579) Psoriasis ( 28537254) Pulse pressure ( 30578418) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 21681796 25663218) White matter hyperintensity volume ( 29752348)
Interacting Genes		20 interacting genes: AP1M2 APP CDC42 CEBPA CYP2C8 ECSIT KBTBD7 MAST1 NTAQ1 NXF1 PDPK1 PGLS RNF32 RPL11 RPL29 TNPO2 TNPO3 TRIM47 TRIO UBE2I	8 interacting genes: APP BLMH BRCA1 CYLD MRFAP1 TRIM8 UBE2D2 UBE2U
Entrez ID		642	91107
HPRD ID		03870	15564
Ensembl ID		ENSG00000108578	ENSG00000132481
Uniprot IDs		Q13867	Q96LD4
PDB IDs		1CB5 2CB5 7V5L 7V5S 7V5T 7XF9
Enriched GO Terms of Interacting Partners?		Cytosol Cytoplasm Postsynapse Intracellular Transport Nuclear Transport Nucleocytoplasmic Transport Nuclear Import Signal Receptor Activity	Protein Polyubiquitination Post-translational Protein Modification Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Modification Process Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Ubiquitin Conjugating Enzyme Activity Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Ubiquitin Protein Ligase Activity Protein Autoubiquitination Negative Regulation Of Interleukin-18-mediated Signaling Pathway Met1-linked Polyubiquitin Deubiquitinase Activity Canonical NF-kappaB Signal Transduction Regulation Of Apoptotic Signaling Pathway Acetylcholine Receptor Activator Activity Macromolecule Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Protein Localization Cysteine-type Aminopeptidase Activity Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Ripoptosome Assembly Ripoptosome Assembly Involved In Necroptotic Process Regulation Of Non-canonical NF-kappaB Signal Transduction PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Mitotic Cell Cycle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Proteolysis Protein Linear Deubiquitination Negative Regulation Of Canonical Wnt Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response
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