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MED16 and LZTR1
Number of citations of the paper that reports this interaction (PMID
20211142
)
148
Data Source:
BioGRID
(two hybrid)
MED16
LZTR1
Gene Name
mediator complex subunit 16
leucine-zipper-like transcription regulator 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Membrane
Mediator Complex
Molecular Function
Transcription Cofactor Activity
Transcription Coactivator Activity
Catalytic Activity
Receptor Activity
Protein Binding
Thyroid Hormone Receptor Coactivator Activity
Vitamin D Receptor Binding
Thyroid Hormone Receptor Binding
Sequence-specific DNA Binding Transcription Factor Activity
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Intracellular Steroid Hormone Receptor Signaling Pathway
Androgen Receptor Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Receptor Activity
Regulation Of Transcription, DNA-templated
Anatomical Structure Morphogenesis
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
CEBPE
CTDP1
ESR1
ESR2
HNF4A
LZTR1
MED9
MYC
50 interactors:
AATF
ANKRD53
ASB12
BMPR1B
CEBPZ
CHAF1A
CNOT6L
E2F8
EHMT1
FANK1
HCLS1
HDAC4
IKBKG
KDM2B
L3MBTL3
MCM3
MED16
MED7
MYBL2
NR1H3
PAPOLG
PARP1
POLR1B
POLR2B
POLR2E
RAI1
RERE
RUVBL1
SCMH1
SND1
SP100
SREBF2
SSX4
STAT1
SUGP2
TAF11
TBX2
TCF19
TFAP2B
TRIM5
TUBGCP4
WWP1
ZBTB1
ZNF137P
ZNF175
ZNF451
ZNF490
ZNF584
ZNF714
ZZZ3
Entrez ID
10025
8216
HPRD ID
06816
08992
Ensembl ID
ENSG00000175221
ENSG00000099949
Uniprot IDs
Q9Y2X0
Q8N653
PDB IDs
Enriched GO Terms of Interacting Partners
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Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Steroid Hormone Mediated Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Cellular Response To Lipid
Vagina Development
Uterus Development
Hormone-mediated Signaling Pathway
Gene Expression
Cellular Macromolecule Biosynthetic Process
Intracellular Estrogen Receptor Signaling Pathway
Macromolecule Biosynthetic Process
Female Genitalia Development
Cellular Response To Steroid Hormone Stimulus
Intracellular Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Prostate Gland Epithelium Morphogenesis
Prostate Gland Morphogenesis
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Response To Lipid
Sex Differentiation
Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Response To Organic Substance
Genitalia Development
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Urogenital System Development
Ovarian Follicle Development
Prostate Gland Development
Cellular Response To Organic Cyclic Compound
Nitrogen Compound Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation
Response To Steroid Hormone
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Regulation Of Gene Expression
Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Macromolecule Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Metabolic Process
Negative Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Process
DNA-templated Transcription, Initiation
Positive Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Metabolic Process
Chromosome Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Viral Process
Chromatin Organization
Viral Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Positive Regulation Of Metabolic Process
Regulation Of Viral Transcription
Chromatin Modification
DNA-templated Transcription, Elongation
Chromatin Remodeling
Positive Regulation Of Viral Transcription
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