MED16

Gene Name		mediator complex subunit 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Mediator Complex
	Molecular Function	Transcription Cofactor Activity Transcription Coactivator Activity Catalytic Activity Receptor Activity Protein Binding Thyroid Hormone Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Activity
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: CEBPE CTDP1 ESR1 ESR2 HNF4A LZTR1 MED9 MYC
Entrez ID		10025
HPRD ID		06816
Ensembl ID		ENSG00000175221
Uniprot IDs		Q9Y2X0
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Steroid Hormone Mediated Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cellular Response To Lipid Vagina Development Uterus Development Hormone-mediated Signaling Pathway Gene Expression Cellular Macromolecule Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Macromolecule Biosynthetic Process Female Genitalia Development Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Lipid Sex Differentiation Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Genitalia Development Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Transcription From RNA Polymerase II Promoter Urogenital System Development Ovarian Follicle Development Prostate Gland Development Cellular Response To Organic Cyclic Compound Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Response To Steroid Hormone
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