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POM121C and STAT5A
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
POM121C
STAT5A
Gene Name
POM121 transmembrane nucleoporin C
signal transducer and activator of transcription 5A
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Pore
Endoplasmic Reticulum Membrane
Nuclear Membrane
Nucleoplasm
Cytosol
Molecular Function
Protein Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Signal Transducer Activity
Protein Binding
Biological Process
Protein Transport
MRNA Transport
Allantoin Metabolic Process
Luteinization
Natural Killer Cell Differentiation
Citrate Metabolic Process
2-oxoglutarate Metabolic Process
Succinate Metabolic Process
Oxaloacetate Metabolic Process
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Isoleucine Metabolic Process
Valine Metabolic Process
Creatine Metabolic Process
Fatty Acid Metabolic Process
JAK-STAT Cascade
Female Pregnancy
Lactation
Peptidyl-tyrosine Phosphorylation
Regulation Of Steroid Metabolic Process
Taurine Metabolic Process
Lipid Storage
Regulation Of Epithelial Cell Differentiation
Positive Regulation Of Natural Killer Cell Differentiation
Negative Regulation Of Mast Cell Apoptotic Process
T Cell Differentiation In Thymus
Prolactin Signaling Pathway
Regulation Of Multicellular Organism Growth
Positive Regulation Of Multicellular Organism Growth
Positive Regulation Of Activated T Cell Proliferation
T Cell Homeostasis
Positive Regulation Of Interleukin-2 Biosynthetic Process
Positive Regulation Of B Cell Differentiation
Positive Regulation Of Gamma-delta T Cell Differentiation
Negative Regulation Of Erythrocyte Differentiation
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
Creatinine Metabolic Process
Development Of Secondary Female Sexual Characteristics
Development Of Secondary Male Sexual Characteristics
Peyer's Patch Development
Positive Regulation Of Inflammatory Response
Positive Regulation Of Mast Cell Differentiation
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Prostate Gland Epithelium Morphogenesis
Epithelial Cell Differentiation Involved In Prostate Gland Development
Mammary Gland Epithelium Development
Positive Regulation Of Mast Cell Proliferation
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Pathways
Signaling by PDGF
Signaling by FGFR in disease
Cytokine Signaling in Immune system
Signaling by ERBB4
Signaling by SCF-KIT
Signaling by Interleukins
Nuclear signaling by ERBB4
Downstream signal transduction
Signaling by FGFR1 mutants
Interleukin-7 signaling
Signaling by FGFR mutants
Interleukin-2 signaling
Prolactin receptor signaling
Signaling by FGFR1 fusion mutants
Interleukin-3, 5 and GM-CSF signaling
Signaling by Leptin
Growth hormone receptor signaling
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
4 interactors:
APC
HINFP
MEOX2
STAT5A
72 interactors:
AQP11
BMX
BRCA1
BRCA2
BTK
CBL
CCR5
CD247
CEBPB
CENPJ
CRK
CRKL
CSNK2B
CTLA4
CYP2C9
EGFR
EP300
EPAS1
EPOR
ERBB4
ESR1
ESR2
FN1
GHR
GLUD1
GNB2
HELZ
IL2RB
IL2RG
IL7R
INSR
JAK1
JAK2
JAK3
KIT
LCK
LEF1
MAGEA12
MAPK1
MAPK3
MRPS6
NARF
NCOR2
NLK
NMI
NR3C1
PDGFRA
PDGFRB
POM121C
POU2F1
PPIB
PPP2CA
PRMT1
PRTFDC1
PTPN1
PTPN11
PTPN2
RBMX
SHC1
SRC
STAP2
STAT1
STAT3
STAT5B
SYK
TCF12
TEK
TSLP
TXNDC11
UGT2B4
WASH2P
ZNF596
Entrez ID
100101267
6776
HPRD ID
19406
03301
Ensembl ID
ENSG00000135213
ENSG00000126561
Uniprot IDs
B4DDR5
B4DET5
A8K6I5
K7EK35
P42229
Q59GY7
PDB IDs
Enriched GO Terms of Interacting Partners
?
T Cell Differentiation In Thymus
Regulation Of Myeloid Leukocyte Differentiation
Positive Regulation Of Mast Cell Differentiation
Regulation Of Epithelial Cell Differentiation
T Cell Differentiation
Regulation Of Myeloid Cell Differentiation
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Epithelium Development
Positive Regulation Of Metabolic Process
Regulation Of Mast Cell Differentiation
Development Of Secondary Male Sexual Characteristics
Cell Cycle Checkpoint
Lymphocyte Differentiation
Negative Regulation Of Odontogenesis
Anterior/posterior Pattern Specification
Positive Regulation Of Transcription, DNA-templated
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Negative Regulation Of Mast Cell Apoptotic Process
Creatinine Metabolic Process
T Cell Aggregation
T Cell Activation
Lymphocyte Aggregation
Leukocyte Aggregation
Regulation Of Mast Cell Apoptotic Process
Somite Specification
Positive Regulation Of Mast Cell Proliferation
Positive Regulation Of Macromolecule Biosynthetic Process
Leukocyte Cell-cell Adhesion
Positive Regulation Of Gene Expression
Isoleucine Metabolic Process
Allantoin Metabolic Process
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Homotypic Cell-cell Adhesion
Leukocyte Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Taurine Metabolic Process
Positive Regulation Of Gamma-delta T Cell Differentiation
Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Negative Regulation Of Erythrocyte Differentiation
Prolactin Signaling Pathway
Positive Regulation Of Cell Adhesion
Tissue Development
Positive Regulation Of Gamma-delta T Cell Activation
Development Of Secondary Female Sexual Characteristics
Urogenital System Development
Valine Metabolic Process
Creatine Metabolic Process
Multicellular Organismal Development
Cellular Response To Organic Substance
Response To Organic Substance
Enzyme Linked Receptor Protein Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Hormone
Cell Surface Receptor Signaling Pathway
Cellular Response To Hormone Stimulus
Protein Autophosphorylation
Cellular Response To Stimulus
Immune Response
Signal Transduction
Immune System Process
Cellular Response To Organonitrogen Compound
Peptidyl-tyrosine Phosphorylation
Signaling
Cell Communication
Cellular Response To Cytokine Stimulus
Regulation Of Immune Response
Defense Response
Response To Cytokine
Positive Regulation Of Cellular Metabolic Process
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Peptidyl-amino Acid Modification
Intracellular Signal Transduction
Growth Hormone Receptor Signaling Pathway
Peptidyl-tyrosine Autophosphorylation
Cellular Response To Peptide Hormone Stimulus
Response To Stimulus
Cellular Response To Growth Hormone Stimulus
Innate Immune Response
Cellular Response To Peptide
Response To Organonitrogen Compound
Regulation Of Immune System Process
Cellular Response To Growth Factor Stimulus
Regulation Of Cell Proliferation
Organ Development
Response To Growth Factor
Cytokine-mediated Signaling Pathway
JAK-STAT Cascade
Regulation Of MAPK Cascade
Response To Peptide Hormone
Neurotrophin TRK Receptor Signaling Pathway
Response To Peptide
Fc Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Kinase Activity
Response To Growth Hormone
Positive Regulation Of Metabolic Process
Neurotrophin Signaling Pathway
Anatomical Structure Development
Tagcloud
?
advantaged
apor
arose
b8
ba
character
coincides
committed
derive
die
dn
epo
epor
erythropoietin
f3epor
homeotic
hox
hypothesize
naturally
normally
preexisting
shortened
subclones
switch
truncated
unexplored
uniquely
Tagcloud (Difference)
?
advantaged
apor
arose
b8
ba
character
coincides
committed
derive
die
dn
epo
epor
erythropoietin
f3epor
homeotic
hox
hypothesize
naturally
normally
preexisting
shortened
subclones
switch
truncated
unexplored
uniquely
Tagcloud (Intersection)
?