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SMC3
Gene Name
structural maintenance of chromosomes 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Chromosome, Centromeric Region
Chromatin
Lateral Element
Spindle Pole
Basement Membrane
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytosol
Cohesin Complex
Cohesin Core Heterodimer
Nuclear Matrix
Meiotic Cohesin Complex
Nuclear Meiotic Cohesin Complex
Molecular Function
Chromatin Binding
Microtubule Motor Activity
Protein Binding
ATP Binding
Mediator Complex Binding
Dynein Binding
Protein Heterodimerization Activity
Biological Process
Mitotic Cell Cycle
Regulation Of DNA Replication
DNA Repair
Mitotic Spindle Organization
Sister Chromatid Cohesion
Mitotic Sister Chromatid Cohesion
Mitotic Nuclear Division
Meiotic Nuclear Division
Signal Transduction
Stem Cell Maintenance
Negative Regulation Of DNA Endoreduplication
Cell Division
Pathways
Establishment of Sister Chromatid Cohesion
Mitotic Prometaphase
Mitotic Telophase/Cytokinesis
Separation of Sister Chromatids
Meiotic synapsis
Cohesin Loading onto Chromatin
Mitotic Anaphase
S Phase
M Phase
Cell Cycle, Mitotic
Resolution of Sister Chromatid Cohesion
Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-protein Interactions
14 interactors:
APC
CEP63
DISC1
FEZ1
FEZ2
KIFAP3
MXD1
MXD3
MXD4
MXI1
RPGR
SMC1A
SMC1B
TRAF3IP1
Entrez ID
9126
HPRD ID
05829
Ensembl ID
ENSG00000108055
Uniprot IDs
Q9UQE7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Microtubule-based Process
Movement Of Cell Or Subcellular Component
Microtubule-based Transport
Cytoskeleton-dependent Intracellular Transport
Negative Regulation Of Cellular Metabolic Process
Cell Projection Morphogenesis
Cell Part Morphogenesis
Microtubule Cytoskeleton Organization
Sister Chromatid Cohesion
Organelle Organization
Intraciliary Transport
Cell Morphogenesis
Cell Cycle Checkpoint
Cell Projection Organization
Negative Regulation Of Cell Proliferation
Positive Regulation Of Calcium-dependent Cell-cell Adhesion
Cell Cycle
Mitotic Nuclear Division
Negative Regulation Of Biosynthetic Process
Microtubule-based Movement
Regulation Of Cell Proliferation
Nervous System Development
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Signal Transduction In Response To DNA Damage
Canonical Wnt Signaling Pathway
Generation Of Neurons
Eye Development
Cellular Localization
Cell Division
Neuron Development
Neurogenesis
Negative Regulation Of Odontogenesis
Organelle Assembly
Cell Cycle Process
Spindle Organization
Regulation Of Cell Projection Organization
Cell Development
Negative Regulation Of DNA Endoreduplication
Negative Regulation Of Transcription, DNA-templated
Axonogenesis
Negative Regulation Of Nucleic Acid-templated Transcription
Cytoskeleton Organization
Neuron Differentiation
Cellular Component Assembly
Negative Regulation Of RNA Biosynthetic Process
Plus-end-directed Vesicle Transport Along Microtubule
Stem Cell Maintenance
Positive Regulation Of Wnt Signaling Pathway
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Axon Development
Tagcloud
?
12q13
1p36
ankrd11
cdls
cleaves
cohesin
cornelia
deeper
discriminating
encompassing
espl1
exome
filtering
hdac8
intellectual
intronic
kbg
lange
merits
mosaic
multisystem
nipbl
novo
partitioning
rad21
recursive
separase
smc1a
undetected