SGPL1

Gene Name		sphingosine-1-phosphate lyase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Sphinganine-1-phosphate Aldolase Activity Carboxy-lyase Activity Pyridoxal Phosphate Binding
	Biological Process	Luteinization Vasculogenesis Kidney Development Fatty Acid Metabolic Process Sphingolipid Metabolic Process Ceramide Metabolic Process Spermatogenesis Androgen Metabolic Process Estrogen Metabolic Process Post-embryonic Development Fibroblast Migration Hemopoiesis Sphingolipid Biosynthetic Process Sphingolipid Catabolic Process Leydig Cell Differentiation Regulation Of Multicellular Organism Growth Small Molecule Metabolic Process Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis Palate Development Face Morphogenesis Apoptotic Signaling Pathway
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs		Pyridoxal Phosphate
Diseases
GWAS
Protein-protein Interactions		1 interactors: TMEM173
Entrez ID		8879
HPRD ID		07224
Ensembl ID		ENSG00000166224
Uniprot IDs		O95470
PDB IDs
Enriched GO Terms of Interacting Partners?		Interferon-beta Production Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Import Into Nucleus, Translocation Cellular Response To Interferon-beta Type I Interferon Production Positive Regulation Of Defense Response To Virus By Host Response To Interferon-beta Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Defense Response To Virus By Host Cellular Response To DsRNA Positive Regulation Of Transcription Factor Import Into Nucleus Response To Exogenous DsRNA Positive Regulation Of Protein Binding Response To DsRNA Positive Regulation Of Type I Interferon Production Regulation Of Defense Response To Virus Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Regulation Of Type I Interferon Production Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Binding Cytokine Production Activation Of Innate Immune Response Regulation Of Protein Binding Defense Response To Virus Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Positive Regulation Of Innate Immune Response Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Transport Regulation Of Innate Immune Response Regulation Of Binding Response To Virus Regulation Of Intracellular Protein Transport Positive Regulation Of Protein Transport Positive Regulation Of Cytokine Production Cellular Response To Organic Cyclic Compound Regulation Of Intracellular Transport Regulation Of Cytokine Production
Tagcloud ?		181b augment bioactive bowel cac chemically colitis colon colonic cyld cylindromatosis degrades enterocytes incompletely irreversibly lyase metabolized micrornas s1p shortening sphingadienes sphingolipid sphingolipids sphingosine spinster spl spns2 stat3 tumorigenic