NLRX1

Description		NLR family member X1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding
	Biological Process	Immune System Process Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of RIG-I Signaling Pathway Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Inflammatory Response
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta Negative regulators of DDX58/IFIH1 signaling Regulation of NF-kappa B signaling
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)
Novel Interacting Genes		8 novel interacting genes: ABCG4 BUD13 C1QTNF5 IFT46 NHERF4 SCN3B TMEM25 TMPRSS4
Interacting Genes		1 interacting genes: SARM1
Entrez ID		79671
HPRD ID		17640
Ensembl ID		ENSG00000160703
Uniprot IDs		A0A9L9PX86 Q86UT6
PDB IDs		3UN9
Enriched GO Terms of Interacting Partners?		NADP+ Nucleosidase Activity Negative Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Extrinsic Component Of Synaptic Membrane NAD+ Nucleosidase Activity Negative Regulation Of Growth Rate Guanylate Cyclase Inhibitor Activity RES Complex Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway NAD+ Catabolic Process ABC-type Sterol Transporter Activity
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