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VDR
Gene Name
vitamin D (1,25- dihydroxyvitamin D3) receptor
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Receptor Complex
RNA Polymerase II Transcription Factor Complex
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Steroid Hormone Receptor Activity
Protein Binding
Zinc Ion Binding
Calcitriol Receptor Activity
Lithocholic Acid Receptor Activity
Sequence-specific DNA Binding
Retinoid X Receptor Binding
Vitamin D Response Element Binding
Calcitriol Binding
Lithocholic Acid Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cell Morphogenesis
Skeletal System Development
Transcription Initiation From RNA Polymerase II Promoter
Calcium Ion Transport
Cellular Calcium Ion Homeostasis
Signal Transduction
Lactation
Negative Regulation Of Cell Proliferation
Gene Expression
Positive Regulation Of Gene Expression
Negative Regulation Of Keratinocyte Proliferation
Positive Regulation Of Vitamin D 24-hydroxylase Activity
Bile Acid Signaling Pathway
Steroid Hormone Mediated Signaling Pathway
Positive Regulation Of Keratinocyte Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Decidualization
Intestinal Absorption
Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution
Regulation Of Calcidiol 1-monooxygenase Activity
Mammary Gland Branching Involved In Pregnancy
Vitamin D Receptor Signaling Pathway
Pathways
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Drugs
Calcitriol
Calcidiol
Ergocalciferol
Cholecalciferol
Paricalcitol
Dihydrotachysterol
Alfacalcidol
Calcipotriol
1alpha,25-Dihydroxyl-20-Epi-22-Oxa-24,26,27-Trihomovitamin D3
Seocalcitol
Inecalcitol
(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
5-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL
1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-protein Interactions
71 interactors:
ACTN4
ACVR1
BAG1
CASC4
CCND3
CDCA7L
CDK7
CFH
CLASRP
COPS2
CREBBP
CSNK2A1
CXXC5
EIF3I
FGR
FOS
FOXO3
GABARAPL1
GABARAPL2
GNPAT
GRIP1
GTF2B
HMGN3
HR
JUN
KDM5A
LCOR
MAPK1
MAPK3
MED1
MED12
MED14
MMRN2
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NKD2
NR0B2
NR1H2
NRIP1
NSD1
POU1F1
POU2F1
PPARG
PPP1CA
PPP2CA
PRCP
PRKCSH
PSMC5
RB1
RNF14
RUNX1
RUNX1T1
RXRA
RXRB
RXRG
SIRT1
SMAD3
SNW1
SRC
SRPK1
STAT1
TAF11
TCF3
TDG
TRIM24
ZBTB16
Entrez ID
7421
HPRD ID
03463
Ensembl ID
ENSG00000111424
Uniprot IDs
F1D8P8
P11473
PDB IDs
1DB1
1IE8
1IE9
1KB2
1KB4
1KB6
1S0Z
1S19
1TXI
1YNW
2HAM
2HAR
2HAS
2HB7
2HB8
3A2I
3A2J
3A3Z
3A40
3A78
3AUQ
3AUR
3AX8
3AZ1
3AZ2
3AZ3
3B0T
3CS4
3CS6
3KPZ
3M7R
3OGT
3P8X
3TKC
3VHW
4G2I
Enriched GO Terms of Interacting Partners
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Transcription, DNA-templated
Positive Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
RNA Metabolic Process
Gene Expression
Positive Regulation Of Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Negative Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Negative Regulation Of Biosynthetic Process
Nitrogen Compound Metabolic Process
Androgen Receptor Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Developmental Process
Cell Communication
Anatomical Structure Development
Signal Transduction
Cellular Response To Stimulus
Response To Hormone
Cellular Metabolic Process
Signaling
Multicellular Organismal Development
Response To Organic Substance
Tagcloud
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3t3
adipocyte
already
arrested
beginning
cloned
clones
differentially
earliest
ebpalpha
hif
hsp105
inducers
l1
master
mrnas
nih
nineteen
place
ppargamma2
preadipocyte
proliferating
regulators
rgs2
rho
seemed
steps
takes
tc10