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APPL2
Gene Name
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endosome Membrane
NuRD Complex
Early Endosome Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Biological Process
Cell Cycle
Signal Transduction
Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
11 interactors:
APPL1
CRADD
MTA2
POT1
RAB22A
RAB5A
RAB5C
RBBP7
RUVBL2
SUV39H2
TINF2
Entrez ID
55198
HPRD ID
06945
Ensembl ID
ENSG00000136044
Uniprot IDs
Q8NEU8
PDB IDs
4H8S
Enriched GO Terms of Interacting Partners
?
Chromatin Remodeling
Chromosome Organization
Rab Protein Signal Transduction
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomere Assembly
Regulation Of Cellular Component Organization
Negative Regulation Of Telomere Maintenance
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Chromatin Assembly Or Disassembly
DNA Metabolic Process
Protein Localization To Chromosome
Telomere Maintenance Via Telomere Lengthening
Regulation Of Chromosome Organization
Chromatin Modification
Ras Protein Signal Transduction
Organelle Organization
Negative Regulation Of Biosynthetic Process
Cellular Protein Localization
Negative Regulation Of DNA Replication
Chromatin Organization
DNA Conformation Change
Telomere Maintenance
ATP-dependent Chromatin Remodeling
Negative Regulation Of Protein ADP-ribosylation
Positive Regulation Of DNA Strand Elongation
Regulation Of Cellular Process
DNA Duplex Unwinding
DNA Geometric Change
Histone Modification
Positive Regulation Of Organelle Organization
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Metabolic Process
Regulation Of Protein ADP-ribosylation
Regulation Of Vesicle Size
Cellular Heat Acclimation
Protein Localization
Response To Abiotic Stimulus
Receptor Internalization Involved In Canonical Wnt Signaling Pathway
Regulation Of Endosome Size
Telomere Formation Via Telomerase
Negative Regulation Of Estrogen Receptor Binding
Transcriptional Activation By Promoter-enhancer Looping
Negative Regulation Of Cellular Metabolic Process
Regulation Of DNA Replication
Negative Regulation Of Protein Glycosylation
Positive Regulation Of DNA Metabolic Process
Histone H3-K9 Dimethylation
Small GTPase Mediated Signal Transduction
Tagcloud
?
adaptor
alanine
appl1
bar
conditional
diminishes
elusive
evoked
fine
glut4
gtpase
homolog
hyperglycemia
likewise
muscles
myotubes
partner
potentiates
rab
serine
skeletal
stimulates
substitution
suppresses
suppressive
tbc1d1
threonine
tune
uptake