PMCH

Name	pro-melanin concentrating hormone
Structure
Interactors	10 interactors: CPE FURIN MCHR1 MCHR2 NPY PCSK1 PCSK2 PCSK5 PCSK6 PCSK7
GO Annotations	Cellular Component	Extracellular Region Nucleus Synapse
	Molecular Function	Hormone Activity Melanin-concentrating Hormone Activity Type 1 Melanin-concentrating Hormone Receptor Binding
	Biological Process	Neuropeptide Signaling Pathway Chemical Synaptic Transmission Spermatogenesis Feeding Behavior Cell Differentiation Negative Regulation Of Synaptic Transmission, Dopaminergic
Pathways	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
GWAS	Adventurousness ( 30643258 ) Brain morphology (MOSTest) ( 32665545 ) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189 ) Height ( 19893584 ) Number of sexual partners ( 30643258 )
Entrez ID	5367
HPRD ID	01459
Ensembl ID	ENSG00000183395
Uniprot IDs	P20382
PDB IDs	8WSS 8WST 8WWK 8WWL 8WWM 8WWN
GO Terms Enriched among Interactors ?	Peptide Hormone Processing Signaling Receptor Ligand Precursor Processing Protein Processing Hormone Metabolic Process Serine-type Peptidase Activity Protein Maturation Serine-type Endopeptidase Activity Peptidase Activity Endopeptidase Activity Regulation Of Hormone Levels Insulin Processing Peptide Metabolic Process Insulin Metabolic Process Neuropeptide Signaling Pathway Peptide Biosynthetic Process Regulation Of Nerve Growth Factor Production Nerve Growth Factor Production Regulation Of Biological Quality Proteolysis Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Viral Life Cycle Extracellular Space Cytokine Precursor Processing Nerve Growth Factor Binding Hydrolase Activity Endomembrane System Signal Peptide Processing Transport Vesicle Secretory Granule Golgi Lumen Secretion By Cell Peptide Binding Secretion Negative Regulation Of Inflammatory Response To Antigenic Stimulus Trans-Golgi Network Protein Metabolic Process Signaling Cell Communication Extracellular Region Golgi Apparatus Melanin-concentrating Hormone Receptor Activity Short-day Photoperiodism Negative Regulation Of Nerve Growth Factor Production Dibasic Protein Processing Zymogen Inhibition Islet Amyloid Polypeptide Processing G Protein-coupled Receptor Signaling Pathway Neuron Projection Cytoplasmic Vesicle