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MCM4
Gene Name
minichromosome maintenance complex component 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Membrane
MCM Complex
Molecular Function
Single-stranded DNA Binding
ATP-dependent DNA Helicase Activity
Protein Binding
ATP Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
Pathways
Synthesis of DNA
G2/M Checkpoints
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
M/G1 Transition
Regulation of DNA replication
Activation of the pre-replicative complex
Orc1 removal from chromatin
S Phase
DNA strand elongation
Cell Cycle, Mitotic
Assembly of the pre-replicative complex
Orc1 removal from chromatin
G1/S Transition
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Switching of origins to a post-replicative state
Unwinding of DNA
Drugs
Diseases
GWAS
Protein-protein Interactions
24 interactors:
CCNA1
CDC5L
CDC7
CDK1
CDK2
CDT1
DBF4
LIG4
MCM2
MCM3
MCM6
MCM7
MCM8
ORC1
ORC2
ORC3
ORC4
ORC5
ORC6
RPA1
RPA2
SSRP1
SUPT16H
TLX2
Entrez ID
4173
HPRD ID
09094
Ensembl ID
ENSG00000104738
Uniprot IDs
B3KMX0
B4DLA6
P33991
PDB IDs
Enriched GO Terms of Interacting Partners
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DNA Replication
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
DNA Metabolic Process
DNA-dependent DNA Replication
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Cell Cycle Process
Cell Cycle
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Response To DNA Damage Stimulus
DNA Repair
Chromosome Organization
Cellular Response To Stress
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Cellular Metabolic Process
DNA Unwinding Involved In DNA Replication
Double-strand Break Repair
Nucleotide-excision Repair, DNA Gap Filling
DNA Duplex Unwinding
DNA Geometric Change
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Cell Cycle Checkpoint
Regulation Of Cell Cycle Phase Transition
DNA Recombination
DNA Conformation Change
Regulation Of Cell Cycle Process
Regulation Of DNA Replication
DNA Recombinase Assembly
Organelle Organization
DNA Damage Checkpoint
Regulation Of DNA-dependent DNA Replication Initiation
Regulation Of Cell Cycle
Metabolic Process
Response To Stress
Positive Regulation Of DNA Replication
Regulation Of Nuclear Cell Cycle DNA Replication
Regulation Of Mitotic Cell Cycle
Tagcloud
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