TSPAN15

Gene Name		tetraspanin 15
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome Tetraspanin-enriched Microdomain
	Molecular Function	Enzyme Binding
	Biological Process	Regulation Of Notch Signaling Pathway Protein Maturation Establishment Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Response to taxane treatment (placlitaxel) ( 23006423)
Protein-protein Interactions		3 interactors: BTRC RGS2 SYNE4
Entrez ID		23555
HPRD ID		15511
Ensembl ID		ENSG00000099282
Uniprot IDs		O95858
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Establishment Of Apical/basal Cell Polarity Negative Regulation Of Phospholipase Activity Polarized Epithelial Cell Differentiation Posttranscriptional Regulation Of Gene Expression Relaxation Of Vascular Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Establishment Of Monopolar Cell Polarity Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Morphogenesis Of An Epithelium Positive Regulation Of Microtubule Polymerization Relaxation Of Cardiac Muscle Negative Regulation Of Smooth Muscle Contraction Establishment Of Epithelial Cell Polarity Tissue Morphogenesis Positive Regulation Of Circadian Rhythm Negative Regulation Of Lipase Activity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Morphogenesis Of A Polarized Epithelium SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Establishment Or Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Smoothened Signaling Pathway Vasodilation Brown Fat Cell Differentiation Epithelium Development Branching Involved In Mammary Gland Duct Morphogenesis Negative Regulation Of Signal Transduction Regulation Of Smooth Muscle Contraction Negative Regulation Of Signaling Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Mammary Gland Duct Morphogenesis Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Microtubule Polymerization Or Depolymerization
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