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SCRIB
Description
scribble planar cell polarity protein
Image
GO Annotations
Cellular Component
Immunological Synapse
Nucleoplasm
Cytoplasm
Plasma Membrane
Cell-cell Junction
Adherens Junction
Postsynaptic Density
Membrane
Basolateral Plasma Membrane
Lamellipodium
Cell Junction
Cell Leading Edge
Scrib-APC-beta-catenin Complex
Myelin Sheath Abaxonal Region
Presynaptic Membrane
Cell Projection
Cell-cell Contact Zone
Synapse
Postsynaptic Membrane
Extracellular Exosome
Anchoring Junction
Presynapse
Postsynapse
Glutamatergic Synapse
Extrinsic Component Of Postsynaptic Density Membrane
Molecular Function
Protein Binding
Protein Kinase Binding
Signaling Adaptor Activity
Cadherin Binding
Biological Process
Establishment Of T Cell Polarity
Neural Tube Closure
Positive Regulation Of Receptor Recycling
Auditory Receptor Cell Morphogenesis
Regulation Of Translation
Intracellular Protein Localization
Cell Population Proliferation
Epithelial Structure Maintenance
Positive Regulation Of Epithelial To Mesenchymal Transition
Synaptic Vesicle Targeting
Morphogenesis Of Embryonic Epithelium
Cell Migration
Cochlear Nucleus Development
Establishment Of Cell Polarity
Cell Differentiation
Polarized Epithelial Cell Differentiation
Positive Regulation Of Type II Interferon Production
Establishment Or Maintenance Of Apical/basal Cell Polarity
Establishment Of Apical/basal Cell Polarity
Post-anal Tail Morphogenesis
Wound Healing
Positive Regulation Of Apoptotic Process
Receptor Clustering
Astrocyte Cell Migration
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Translational Initiation
Negative Regulation Of Activated T Cell Proliferation
Synaptic Vesicle Endocytosis
Positive Chemotaxis
Auditory Receptor Cell Stereocilium Organization
Inner Ear Receptor Cell Stereocilium Organization
Apoptotic Process Involved In Morphogenesis
Mammary Gland Duct Morphogenesis
Protein Localization To Adherens Junction
Activation Of GTPase Activity
Cell-cell Adhesion
Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
Vesicle-mediated Transport In Synapse
Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways
Asymmetric localization of PCP proteins
CDC42 GTPase cycle
RHOQ GTPase cycle
RHOJ GTPase cycle
RND3 GTPase cycle
RND2 GTPase cycle
Drugs
Diseases
GWAS
Menarche (age at onset) (
25231870
)
Interacting Genes
18 interacting genes:
ACE2
ACVR2B
APC
ARHGEF7
BRSK2
C5AR2
DYRK1A
EXOSC10
LPP
MAPK3
OGT
PRKCA
STX4
TJP2
TRIP6
TSHR
UBE3A
VANGL2
Entrez ID
23513
HPRD ID
06984
Ensembl ID
ENSG00000180900
Uniprot IDs
A0A0G2JNZ2
A0A0G2JPP5
A0PJK8
Q14160
PDB IDs
1UJU
1WHA
1X5Q
2W4F
4WYT
4WYU
5VWC
5VWI
5VWK
6EEY
6ESP
6MS1
6MTU
6MTV
6MYE
6MYF
6XA6
6XA7
6XA8
7JO7
7QRS
7QRT
7QS8
7QS9
7QSA
7QSB
7QTO
7QTP
7QTU
8B82
8B87
8B8O
8B9T
8BIA
8BJ0
8CD3
Enriched GO Terms of Interacting Partners
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Regulation Of Cell Motility
Regulation Of Cell Migration
Anchoring Junction
Regulation Of Locomotion
Regulation Of Cell Communication
Regulation Of Cold-induced Thermogenesis
Regulation Of Signaling
Positive Regulation Of Locomotion
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Regulation Of Signal Transduction
Protein Serine/threonine Kinase Activity
Regulation Of Cellular Component Organization
Plasma Membrane
Regulation Of Biological Quality
Cell Junction Organization
Negative Regulation Of Microtubule Polymerization
Stress Fiber
Protein Kinase Activity
Cell Junction Assembly
Regulation Of TORC1 Signaling
Regulation Of Microtubule Polymerization Or Depolymerization
Positive Regulation Of Cold-induced Thermogenesis
Regulation Of Hormone Levels
Regulation Of Cytoskeleton Organization
Signal Transduction
Intracellular Signal Transduction
Regulation Of Protein Localization
Tau-protein Kinase Activity
Glutamatergic Synapse
Kinase Activity
Negative Regulation Of Protein-containing Complex Assembly
Focal Adhesion Assembly
Protein Serine/threonine/tyrosine Kinase Activity
Protein Phosphorylation
Response To Stress
Protein Serine Kinase Activity
System Development
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Cytoskeleton Organization
Regulation Of TOR Signaling
Negative Regulation Of Supramolecular Fiber Organization
Phosphorylation
Negative Regulation Of Cellular Component Organization
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Insulin Secretion
Negative Regulation Of Metabolic Process
Cell-cell Junction Organization
Positive Regulation Of Metabolic Process
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