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SCRIB
Gene Name
scribbled planar cell polarity protein
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Plasma Membrane
Cell-cell Junction
Cell-cell Adherens Junction
Basolateral Plasma Membrane
Lamellipodium
Cell Leading Edge
Scrib-APC-beta-catenin Complex
Myelin Sheath Abaxonal Region
Presynaptic Membrane
Postsynaptic Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Biological Process
Neural Tube Closure
Positive Regulation Of Receptor Recycling
Asymmetric Protein Localization
Cell Proliferation
Viral Process
Synaptic Vesicle Targeting
Single Organismal Cell-cell Adhesion
Cell Migration
Cochlear Nucleus Development
Activation Of Rac GTPase Activity
Establishment Of Apical/basal Cell Polarity
Wound Healing
Positive Regulation Of Apoptotic Process
Astrocyte Cell Migration
Negative Regulation Of Mitotic Cell Cycle
Synaptic Vesicle Endocytosis
Positive Chemotaxis
Auditory Receptor Cell Stereocilium Organization
Apoptotic Process Involved In Morphogenesis
Mammary Gland Duct Morphogenesis
Protein Localization To Adherens Junction
Pathways
Asymmetric localization of PCP proteins
Signaling by Wnt
PCP/CE pathway
beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Protein-protein Interactions
11 interactors:
APC
ARHGEF7
EXOSC10
LPP
MAPK3
PRKCA
STX4
TJP2
TRIP6
TSHR
UBE3A
Entrez ID
23513
HPRD ID
06984
Ensembl ID
ENSG00000180900
Uniprot IDs
A0PJK8
Q14160
PDB IDs
1UJU
1WHA
1X5Q
2W4F
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cell Migration
Regulation Of Locomotion
Positive Regulation Of Cell Motility
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Cell Junction Assembly
Cell-cell Junction Organization
Regulation Of Cell Migration
Regulation Of Cell Motility
Cell Activation
Regulation Of Cellular Component Movement
Positive Regulation Of Cell Adhesion
Apoptotic Process
Epidermal Growth Factor Receptor Signaling Pathway
Programmed Cell Death
Regulation Of Intracellular Signal Transduction
ERBB Signaling Pathway
Regulation Of Cellular Localization
Cell Death
Regulation Of Signal Transduction
Death
Signaling
Platelet Activation
Cell Communication
Focal Adhesion Assembly
Cell Adhesion
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Signaling
Neurotrophin Signaling Pathway
Regulation Of Cell Adhesion
Positive Regulation Of Signal Transduction
Adherens Junction Assembly
Cell-substrate Junction Assembly
Regulation Of Protein Localization
Positive Regulation Of Intracellular Signal Transduction
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Signal Transduction
Sperm Entry
Negative Regulation Of Apolipoprotein Binding
Positive Regulation Of Dense Core Granule Biogenesis
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Execution Phase Of Apoptosis
Neuron Development
Response To Interleukin-1
Adherens Junction Organization
Cell Development
Blood Coagulation
Hemostasis
Intracellular Signal Transduction
Positive Regulation Of Eosinophil Degranulation
Tagcloud
?
asymmetry
complex
conserved
crb
crb3
crumbs
defective
dysregulation
epithelium
fate
focus
homolog
invasion
kidney
mainly
mammary
member
migration
mouse
numerous
organelle
par
partitioning
polarity
roles
shape
suppressor
transport