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F2RL1
Gene Name
coagulation factor II (thrombin) receptor-like 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Early Endosome
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Pseudopodium
Molecular Function
G-protein Alpha-subunit Binding
Receptor Activity
G-protein Coupled Receptor Activity
Receptor Binding
Protein Binding
Thrombin Receptor Activity
G-protein Beta-subunit Binding
Biological Process
T Cell Activation Involved In Immune Response
Positive Regulation Of Leukocyte Chemotaxis
Positive Regulation Of Cytokine Secretion Involved In Immune Response
Positive Regulation Of Glomerular Filtration
Inflammatory Response
G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Blood Coagulation
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Blood Coagulation
Positive Regulation Of Cell Migration
Positive Regulation Of Actin Filament Depolymerization
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of Toll-like Receptor 2 Signaling Pathway
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Rho Protein Signal Transduction
Chemokine (C-C Motif) Ligand 2 Secretion
Neutrophil Activation
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Eosinophil Degranulation
Innate Immune Response
Positive Regulation Of Vasodilation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of JNK Cascade
Negative Regulation Of JNK Cascade
Positive Regulation Of JNK Cascade
Interleukin-1 Beta Secretion
Leukocyte Migration
Positive Regulation Of Chemotaxis
Positive Regulation Of Positive Chemotaxis
Defense Response To Virus
Positive Regulation Of Phagocytosis, Engulfment
Establishment Of Endothelial Barrier
Positive Regulation Of ERK1 And ERK2 Cascade
Thrombin Receptor Signaling Pathway
Leukocyte Proliferation
Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Interleukin-10 Secretion
Interferon-gamma Secretion
Chemokine Secretion
Negative Regulation Of Chemokine Secretion
Mature Conventional Dendritic Cell Differentiation
Positive Regulation Of Renin Secretion Into Blood Stream
Positive Regulation Of Interleukin-8 Secretion
Positive Regulation Of Interleukin-6 Secretion
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions
11 interactors:
CAPN1
CAPN2
CBL
COPS5
CTSG
ELANE
F2
GPRASP1
PLG
PRTN3
ST14
Entrez ID
2150
HPRD ID
02960
Ensembl ID
ENSG00000164251
Uniprot IDs
P55085
PDB IDs
Enriched GO Terms of Interacting Partners
?
Proteolysis
Extracellular Matrix Disassembly
Protein Metabolic Process
Killing By Host Of Symbiont Cells
Negative Regulation Of Fibrinolysis
Receptor Catabolic Process
Regulation Of Fibrinolysis
Extracellular Matrix Organization
Extracellular Structure Organization
Neutrophil Mediated Immunity
Killing Of Cells Of Other Organism
Catabolic Process
Negative Regulation Of Growth Of Symbiont In Host
Defense Response To Fungus
Fibrinolysis
Positive Regulation Of Blood Coagulation
Interaction With Symbiont
Leukocyte Mediated Cytotoxicity
Leukocyte Migration
Positive Regulation Of Coagulation
Response To Fungus
Positive Regulation Of Wound Healing
Negative Regulation Of Blood Coagulation
Regulation Of Cell Proliferation
Negative Regulation Of Coagulation
Positive Regulation Of Cell Proliferation
Collagen Catabolic Process
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Wound Healing
Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Acute Inflammatory Response
Receptor Metabolic Process
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Regulation Of Phosphatidylinositol 3-kinase Signaling
Multicellular Organismal Metabolic Process
Blood Coagulation
Hemostasis
Neutrophil Mediated Killing Of Gram-positive Bacterium
Neutrophil Mediated Killing Of Fungus
G-protein Coupled Receptor Catabolic Process
Regulation Of Blood Coagulation
Mononuclear Cell Migration
Regulation Of Wound Healing
Immune System Process
Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Exosomal Secretion
Positive Regulation Of Fibrinolysis
Regulation Of Body Fluid Levels
Response To Stress
Tagcloud
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