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PLK3
Gene Name
polo-like kinase 3
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Cytoplasm
Golgi Stack
Centrosome
Dendrite
Neuronal Cell Body
Molecular Function
P53 Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Response To Reactive Oxygen Species
Protein Phosphorylation
Apoptotic Process
Response To Osmotic Stress
Cellular Response To DNA Damage Stimulus
Mitotic Cell Cycle Checkpoint
Endomitotic Cell Cycle
Response To Radiation
Cytoplasmic Microtubule Organization
Regulation Of Cytokinesis
Negative Regulation Of Apoptotic Process
Protein Kinase B Signaling
Mitotic G1/S Transition Checkpoint
Regulation Of Cell Division
Golgi Disassembly
Positive Regulation Of Intracellular Protein Transport
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Involved In Cellular Response To Hypoxia
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
14 interactors:
AURKA
CDC25C
CENPU
CHEK2
CIB1
MAP2K1
MAPK1
POU2F1
SNCA
SNCB
SUMO1
TP53
TRIP13
VRK1
Entrez ID
1263
HPRD ID
04222
Ensembl ID
ENSG00000173846
Uniprot IDs
Q9H4B4
PDB IDs
4B6L
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Mitotic Cell Cycle
Organelle Organization
Regulation Of Cellular Component Organization
Regulation Of Organelle Organization
Cellular Response To Stress
Regulation Of Protein Metabolic Process
Mitotic Nuclear Division
Cell Cycle Process
Regulation Of Protein Stability
Positive Regulation Of Cellular Protein Metabolic Process
Mitotic Cell Cycle Process
Double-strand Break Repair
Regulation Of Golgi Inheritance
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Regulation Of Metabolic Process
Cell Division
Regulation Of Intracellular Transport
Regulation Of Cellular Protein Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Response To DNA Damage Stimulus
Cellular Metabolic Process
Regulation Of Golgi Organization
Golgi Inheritance
Cell Aging
Regulation Of Microtubule Polymerization Or Depolymerization
Cellular Response To Growth Factor Stimulus
Female Meiosis I
DNA Repair
Response To Growth Factor
Positive Regulation Of Protein Serine/threonine Kinase Activity
DNA Metabolic Process
Regulation Of Protein Phosphorylation
Developmental Process
Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Early Endosome To Late Endosome Transport
Regulation Of RNA Metabolic Process
Positive Regulation Of Metabolic Process
Aging
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Protein Phosphorylation
Peptidyl-serine Phosphorylation
Replicative Senescence
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Protein Kinase Activity
Histone-serine Phosphorylation
Tagcloud
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3a
5mum
5ng
annotation
correlating
crosstalk
doxo
dusp5
etv7
fc
fluoruracil
inducer
lamp3
log2
mcf7
microenvironment
modify
nfkappab
ntn1
nutlin
opposite
proof
qpcr
repressed
snai1
synergistically
tnfalpha
transcriptome
unc5b