GIT2 and RUFY1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GIT2	RUFY1
Description		GIT ArfGAP 2	RUN and FYVE domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity	Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)	Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		9815	80230
HPRD ID		09779	15282
Ensembl ID		ENSG00000139436	ENSG00000176783
Uniprot IDs		F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58	A8K7B1 Q96T51
PDB IDs			2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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