GIT2 and C4BPA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GIT2	C4BPA
Description		GIT ArfGAP 2	complement component 4 binding protein alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Extracellular Region Extracellular Space Plasma Membrane Blood Microparticle
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity	Complement Activation, Classical Pathway Response To Symbiotic Bacterium Innate Immune Response Positive Regulation Of Protein Catabolic Process Negative Regulation Of Complement Activation, Classical Pathway Regulation Of Opsonization
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle	Regulation of Complement cascade
Drugs			Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)	Bell's palsy ( 33602968) Blood protein levels ( 29875488) C4b binding protein levels ( 20212171) Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Venous thromboembolism ( 31420334 31676865)
Interacting Genes		48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	10 interacting genes: APCS BMPR2 FXYD6 GIT2 GTF2I HSP90AA1 LBP LRP1 PROS1 SMARCD1
Entrez ID		9815	722
HPRD ID		09779	00403
Ensembl ID		ENSG00000139436	ENSG00000123838
Uniprot IDs		F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58	P04003
PDB IDs			2A55 4B0F 5HYP 5HYT 5HYU 5HZP 5I0Q
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?