RUFY1 and RAB3IP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RUFY1	RAB3IP
Description		RUN and FYVE domain containing 1	RAB3A interacting protein
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GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle	Nucleus Microtubule Organizing Center Cytosol Lamellipodium Golgi To Plasma Membrane Transport Vesicle
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis	Protein Targeting To Membrane Exocytosis Regulation Of Catalytic Activity Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		Synthesis of PIPs at the plasma membrane	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25	33 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A GPD2 KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76
Entrez ID		80230	117177
HPRD ID		15282	10565
Ensembl ID		ENSG00000176783	ENSG00000127328
Uniprot IDs		A8K7B1 Q96T51	Q96QF0
PDB IDs		2YQM 2YW8	4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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