RUFY1 and RAB39B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		RUFY1	RAB39B
Description		RUN and FYVE domain containing 1	RAB39B, member RAS oncogene family
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GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Golgi Apparatus Plasma Membrane Cytoplasmic Vesicle Membrane Vesicle Neuron Projection
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Myosin V Binding
	Biological Process	Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis	Autophagy Regulation Of Autophagy Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Synapse Organization
Pathways		Synthesis of PIPs at the plasma membrane	RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25	6 interacting genes: GOLGA2 RAB3GAP1 RUFY1 SGSM3 VPS26C ZDHHC17
Entrez ID		80230	116442
HPRD ID		15282	06703
Ensembl ID		ENSG00000176783	ENSG00000155961
Uniprot IDs		A8K7B1 Q96T51	Q96DA2
PDB IDs		2YQM 2YW8	6S5F
Enriched GO Terms of Interacting Partners?
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