GIT2 and RUSC2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GIT2	RUSC2
Description		GIT ArfGAP 2	RUN and SH3 domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Cytosol Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding Small GTPase Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Catalytic Activity	Biological_process
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOU GTPase cycle RAC3 GTPase cycle RHOV GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolic syndrome ( 20694148) Metabolite levels ( 23823483) Metabolite levels (MHPG) ( 23319000)	Psoriasis ( 25903422)
Interacting Genes		48 interacting genes: ACTG1 ACTN1 ARHGEF6 ARHGEF7 ATF5 C4BPA CALCOCO2 CDC42 CORO1A E2F2 EDC4 GCH1 GET4 GIT1 GRK2 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LAMTOR5 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	11 interacting genes: DLST EGFR FXR1 GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SIGMAR1 SRPRA
Entrez ID		9815	9853
HPRD ID		09779	18009
Ensembl ID		ENSG00000139436	ENSG00000198853
Uniprot IDs		F8VXI9 F8W822 Q14161 Q68DM7 Q6FI58	Q8N2Y8
PDB IDs			6IF2
Enriched GO Terms of Interacting Partners?
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