RUFY1 and UTP25

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		RUFY1	UTP25
Description		RUN and FYVE domain containing 1	UTP25 small subunit processor component
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Nucleolus Small-subunit Processome
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding	RNA Binding Protein Binding RRNA Binding U3 SnoRNA Binding
	Biological Process	Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Catabolic Process Protein Destabilization Positive Regulation Of Embryonic Development Embryonic Organ Development Protein Localization To Nucleolus
Pathways		Synthesis of PIPs at the plasma membrane	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25	11 interacting genes: AP2M1 APP CEP70 MAGEA11 MEOX2 MID2 MIPOL1 RUFY1 TRIM62 TRIM9 ZBTB10
Entrez ID		80230	27042
HPRD ID		15282	14535
Ensembl ID		ENSG00000176783	ENSG00000117597
Uniprot IDs		A8K7B1 Q96T51	Q68CQ4
PDB IDs		2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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