NEK9 and NEK7

Number of citations of the paper that reports this interaction (PubMedID 27173435)
78

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		NEK9	NEK7
Description		NIMA related kinase 9	NIMA related kinase 7
Image
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol	Spindle Pole Nucleoplasm Cytoplasm Microtubule Organizing Center Microtubule
	Molecular Function	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Cell Cycle Cell Division	Protein Phosphorylation Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Via Telomerase Spindle Assembly Positive Regulation Of Telomerase Activity Positive Regulation Of Telomere Capping
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs		Fostamatinib
Diseases
GWAS		Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)	Age at first sexual intercourse ( 34211149) Height ( 28552196) High altitude adaptation ( 28373541) Pulse pressure ( 33230300)
Interacting Genes		21 interacting genes: BICD2 CSN2 GABARAP GZMB IFT43 JDP2 LIN52 MALL MAP1LC3B MBP NEK6 NEK7 NEK8 PALS1 RAN RARG RPS6KL1 SSRP1 SUPT16H TTN WDR33	8 interacting genes: C1orf53 EML4 LYN NEK9 PPP1R13B TERF1 TNNI1 ZBTB41
Entrez ID		91754	140609
HPRD ID		11386	06027
Ensembl ID		ENSG00000119638	ENSG00000151414
Uniprot IDs		A0A7I2V454 A0A7I2V5R1 Q6PKF2 Q8TD19	B2R8K8 Q8TDX7
PDB IDs		3ZKE 3ZKF	2WQM 2WQN 5DE2 6NPY 6S73 6S75 6S76
Enriched GO Terms of Interacting Partners?
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