NEK9 and GABARAP

Number of citations of the paper that reports this interaction (PubMedID 31857374)
10

Data Source:
BioGRID (affinity chromatography technology, pull down, unspecified method, affinity chromatography technology)

		NEK9	GABARAP
Description		NIMA related kinase 9	GABA type A receptor-associated protein
Image
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece
	Molecular Function	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Protein Phosphorylation Cell Cycle Cell Division	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	Macroautophagy TBC/RABGAPs
Drugs		Fostamatinib
Diseases
GWAS		Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)	Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		21 interacting genes: BICD2 CSN2 GABARAP GZMB IFT43 JDP2 LIN52 MALL MAP1LC3B MBP NEK6 NEK7 NEK8 PALS1 RAN RARG RPS6KL1 SSRP1 SUPT16H TTN WDR33	61 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 ATXN3 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GJA1 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 MYBPC2 NBR1 NEDD4 NEK9 NSF OPTN PCM1 PGS1 PKP4 PRKCZ RB1CC1 SEC62 SNX18 SQSTM1 SRPK1 SRPK2 STK3 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TRIM32 TSR2 TTN TUBB3 ULK1 ULK2 VPS28
Entrez ID		91754	11337
HPRD ID		11386	05496
Ensembl ID		ENSG00000119638	ENSG00000170296
Uniprot IDs		A0A7I2V454 A0A7I2V5R1 Q6PKF2 Q8TD19	O95166 Q6IAW1
PDB IDs		3ZKE 3ZKF	1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO 7BRQ 7BRT 7BRU 7BV4
Enriched GO Terms of Interacting Partners?
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