NEK7 and NEK9

Number of citations of the paper that reports this interaction (PubMedID 27173435)
78

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		NEK7	NEK9
Description		NIMA related kinase 7	NIMA related kinase 9
Image
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Microtubule Organizing Center Microtubule	Nucleus Centrosome Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Via Telomerase Spindle Assembly Positive Regulation Of Telomerase Activity Positive Regulation Of Telomere Capping	Protein Phosphorylation Cell Cycle Cell Division
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs			Fostamatinib
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Height ( 28552196) High altitude adaptation ( 28373541) Pulse pressure ( 33230300)	Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)
Interacting Genes		8 interacting genes: C1orf53 EML4 LYN NEK9 PPP1R13B TERF1 TNNI1 ZBTB41	21 interacting genes: BICD2 CSN2 GABARAP GZMB IFT43 JDP2 LIN52 MALL MAP1LC3B MBP NEK6 NEK7 NEK8 PALS1 RAN RARG RPS6KL1 SSRP1 SUPT16H TTN WDR33
Entrez ID		140609	91754
HPRD ID		06027	11386
Ensembl ID		ENSG00000151414	ENSG00000119638
Uniprot IDs		B2R8K8 Q8TDX7	A0A7I2V454 A0A7I2V5R1 Q6PKF2 Q8TD19
PDB IDs		2WQM 2WQN 5DE2 6NPY 6S73 6S75 6S76	3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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