NEK7 and TNNI1

		NEK7	TNNI1
Description		NIMA related kinase 7	troponin I1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Microtubule Organizing Center Microtubule	Cytosol Troponin Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity	Actin Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Via Telomerase Spindle Assembly Positive Regulation Of Telomerase Activity Positive Regulation Of Telomere Capping	Skeletal Muscle Contraction Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	Striated Muscle Contraction
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Height ( 28552196) High altitude adaptation ( 28373541) Pulse pressure ( 33230300)
Interacting Genes		8 interacting genes: C1orf53 EML4 LYN NEK9 PPP1R13B TERF1 TNNI1 ZBTB41	48 interacting genes: ACTA1 ANKRD11 ARMC7 C2orf68 CABP2 CABP5 CCDC102B CCDC57 CCDC85B CDCA7L CEP19 CETN3 CTNNA3 DCAF11 DCC EAF1 EFCAB2 EIF1AD EIF3B ENKD1 ESRRG KIFC3 L3MBTL2 MBD3 MCRS1 MDFI MNS1 MTUS2 NEK7 PIH1D2 PIK3R3 PKD2L1 PNMA1 POLR1C PRKAB2 SAT1 SCNM1 SPANXN2 SYCE1L TNNC1 TNNT1 TNNT2 TPM3 TRIM41 TRIM55 TRIM63 USP20 ZNF76
Entrez ID		140609	7135
HPRD ID		06027	01842
Ensembl ID		ENSG00000151414	ENSG00000159173
Uniprot IDs		B2R8K8 Q8TDX7	P19237
PDB IDs		2WQM 2WQN 5DE2 6NPY 6S73 6S75 6S76
Enriched GO Terms of Interacting Partners?
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