ASAP3 and PDZD3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		ASAP3	PDZD3
Description		ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	PDZ domain containing 3
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GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding
	Biological Process	Cell Migration Positive Regulation Of GTPase Activity Regulation Of Stress Fiber Assembly	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane
Pathways			Intestinal infectious diseases
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) LDL cholesterol levels ( 32203549) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549)
Interacting Genes		9 interacting genes: ARF6 CRK MTNR1A PDZD3 REL TCF4 TEPSIN TFCP2 UBE3A	21 interacting genes: ABCC2 ASAP3 CACNA1S CFTR FCER1G GUCY2C NLRX1 NOMO1 PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8
Entrez ID		55616	79849
HPRD ID		11662	06191
Ensembl ID		ENSG00000088280	ENSG00000172367
Uniprot IDs		A0A024RAB1 B4DRP2 Q8TDY4	B0YJ61 Q86UT5
PDB IDs		2B0O 3LVQ 3LVR	2V90
Enriched GO Terms of Interacting Partners?
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