KIF9 and ALAS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KIF9	ALAS1
Description		kinesin family member 9	5'-aminolevulinate synthase 1
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Cytoplasm Kinesin Complex Microtubule Vesicle	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Identical Protein Binding	5-aminolevulinate Synthase Activity Protein Binding Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	Microtubule-based Movement Extracellular Matrix Disassembly Regulation Of Podosome Assembly Organelle Disassembly	Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Hemoglobin Biosynthetic Process Erythrocyte Development
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins	Heme biosynthesis PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis
Drugs			Pyridoxal phosphate Pyridoxal phosphate Glycine
Diseases
GWAS		Adiponectin levels ( 31178129) Huntington's disease progression ( 28642124) Platelet count ( 32888494) Platelet distribution width ( 32888494) Refractive error ( 32231278) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872)
Interacting Genes		63 interacting genes: ACBD4 ALAS1 AMOTL2 ATP5IF1 BLZF1 CARD9 CCDC125 CYTIP DISC1 EFHC2 EMD FXR1 GOLGA6A HMBOX1 HOOK2 HSF2BP IHO1 IKZF1 IKZF3 INKA1 IQCB1 JAKMIP2 KANK2 KCTD9 KRT75 KRTAP10-3 KRTAP10-6 KRTAP10-9 LZTS1 LZTS2 MAD1L1 MID1 MID2 MIPOL1 NAB2 OIP5 OOEP PIBF1 PNMA5 PPP1R13B PRICKLE1 PRMT6 RBM48 RBM5 ROPN1 SHISA6 SLAIN1 SSX2IP STEEP1 TFIP11 TRIM27 TRIM37 TRIM54 VIM VPS52 ZBTB8A ZC2HC1C ZCCHC7 ZNF417 ZNF436 ZNF566 ZNF572 ZRANB1	55 interacting genes: BCL7A C2orf42 C8orf33 CAP2 CCHCR1 CDC73 CDK5 CDKN1A CERK COBL DUSP19 EP400 FBXL8 FXR1 GNL3L GRXCR1 HSBP1L1 JRK KIF9 KLHL35 LONRF1 LRRC45 MTFR2 MTSS2 NUDT3 OXTR PIBF1 PIK3CB PLAU POLDIP2 PPL RAP1B RNF168 RTL8B SH2D4A SNRPB2 SNX20 STAMBP SUMO2 TCEA2 TEKT4 TK1 TMSB10 TMSB4X TMSB4XP1 TMSB4XP2 TMSB4XP6 TTC23 USP20 UTP14C WIPF1 ZFYVE26 ZMAT1 ZNF175 ZNF564
Entrez ID		64147	211
HPRD ID		07444	00505
Ensembl ID		ENSG00000088727	ENSG00000023330
Uniprot IDs		A8K932 Q9HAQ2	B4DVA0 P13196 Q5JAM2
PDB IDs		3NWN
Enriched GO Terms of Interacting Partners?
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