ALAS1 and ZMAT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		ALAS1	ZMAT1
Description		5'-aminolevulinate synthase 1	zinc finger matrin-type 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol	Nucleus
	Molecular Function	5-aminolevulinate Synthase Activity Protein Binding Pyridoxal Phosphate Binding Identical Protein Binding	DNA Binding Zinc Ion Binding
	Biological Process	Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Hemoglobin Biosynthetic Process Erythrocyte Development
Pathways		Heme biosynthesis PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis
Drugs		Pyridoxal phosphate Pyridoxal phosphate Glycine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Parkinson's disease ( 28892059) Schizophrenia ( 23974872)
Interacting Genes		55 interacting genes: BCL7A C2orf42 C8orf33 CAP2 CCHCR1 CDC73 CDK5 CDKN1A CERK COBL DUSP19 EP400 FBXL8 FXR1 GNL3L GRXCR1 HSBP1L1 JRK KIF9 KLHL35 LONRF1 LRRC45 MTFR2 MTSS2 NUDT3 OXTR PIBF1 PIK3CB PLAU POLDIP2 PPL RAP1B RNF168 RTL8B SH2D4A SNRPB2 SNX20 STAMBP SUMO2 TCEA2 TEKT4 TK1 TMSB10 TMSB4X TMSB4XP1 TMSB4XP2 TMSB4XP6 TTC23 USP20 UTP14C WIPF1 ZFYVE26 ZMAT1 ZNF175 ZNF564	23 interacting genes: ABL2 ALAS1 BLK BLZF1 C1orf109 CDC23 DUSP21 EXOSC5 GOLGA2 GORASP2 GRB2 HOXA1 LZTS2 MYO15B OIP5 PIK3R3 QRICH1 RFC5 RUNX1T1 SAXO1 SCNM1 STK16 ZNF124
Entrez ID		211	84460
HPRD ID		00505	10029
Ensembl ID		ENSG00000023330	ENSG00000166432
Uniprot IDs		B4DVA0 P13196 Q5JAM2	A0A494C0A7 A7MD47 Q5H9K5
PDB IDs
Enriched GO Terms of Interacting Partners?
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