ATP6V1A and GON4L

		ATP6V1A	GON4L
Description		ATPase H+ transporting V1 subunit A	gon-4 like
Image			No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Transport Vesicle Secretory Granule Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	Protein Binding ATP Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Transcription Coregulator Activity Transcription Corepressor Activity
	Biological Process	Cellular Iron Ion Homeostasis ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Proton Transmembrane Transport	Regulation Of Transcription, DNA-templated B Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Prostate cancer ( 23535732)	Blood urea nitrogen levels ( 31152163) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lewy body disease ( 25188341) Neuritic plaque ( 31497858) Periventricular white matter hyperintensities ( 32517579) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528)
Interacting Genes		15 interacting genes: ANXA7 CD200R1L CDC42 CDKN1A GCH1 GON4L KCNJ9 LPGAT1 LSAMP PPM1D RALGAPA1 SMN1 TK1 TMPRSS7 TUFM	2 interacting genes: ATP6V1A ITGB5
Entrez ID		523	54856
HPRD ID		06120	13370
Ensembl ID		ENSG00000114573	ENSG00000116580
Uniprot IDs		P38606	A4PB67 A4PB68 Q14BN2 Q3T8J9 Q9H986
PDB IDs		6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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