GON4L and ITGB5

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		GON4L	ITGB5
Description		gon-4 like	integrin subunit beta 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Integrin Alphav-beta5 Complex Receptor Complex Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity Transcription Corepressor Activity	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity
	Biological Process	Regulation Of Transcription, DNA-templated B Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Migration Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Stress Fiber Assembly Viral Entry Into Host Cell Epithelial Cell-cell Adhesion
Pathways			Cross-presentation of particulate exogenous antigens (phagosomes) Molecules associated with elastic fibres Integrin cell surface interactions Integrin cell surface interactions Syndecan interactions Syndecan interactions ECM proteoglycans Smooth Muscle Contraction
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lewy body disease ( 25188341) Neuritic plaque ( 31497858) Periventricular white matter hyperintensities ( 32517579) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528)	Airway hyperresponsiveness ( 23984888) Carpal tunnel syndrome ( 30833571) Coronary artery disease ( 28714974) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin concentration ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		2 interacting genes: ATP6V1A ITGB5	58 interacting genes: ANXA5 APPBP2 CCN1 CYSRT1 DAB1 DAB2 DOK1 EFEMP2 EHMT2 EPS8 EWSR1 FDFT1 FHL2 FHL3 FLNA GAPDH GOLGA2 GON4L ITGA5 ITGAV ITGB3BP KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP5-7 LTBP1 LTBP3 MTDH MTUS2 MYBPC2 MYO10 NBPF19 NOTCH2NLA NUMB P2RY2 PAK4 PALLD PPARD PTK2 RACK1 SNTA1 SPP1 SRSF9 STAB2 TAF1 TLN1 TNS2 TRIM55 TRIM63 TTN ZBTB17 ZNF655
Entrez ID		54856	3693
HPRD ID		13370	00949
Ensembl ID		ENSG00000116580	ENSG00000082781
Uniprot IDs		A4PB67 A4PB68 Q14BN2 Q3T8J9 Q9H986	D3DNA1 L7RT22 P18084
PDB IDs
Enriched GO Terms of Interacting Partners?
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