ATP6V1A and LPGAT1

		ATP6V1A	LPGAT1
Description		ATPase H+ transporting V1 subunit A	lysophosphatidylglycerol acyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Transport Vesicle Secretory Granule Intracellular Membrane-bounded Organelle Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	1-acylglycerol-3-phosphate O-acyltransferase Activity 2-acylglycerol O-acyltransferase Activity Acyltransferase Activity 2-acylglycerol-3-phosphate O-acyltransferase Activity Lysophospholipid Acyltransferase Activity
	Biological Process	Cellular Iron Ion Homeostasis ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Proton Transmembrane Transport	Phospholipid Biosynthetic Process Triglyceride Biosynthetic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling Positive Regulation Of Fatty Acid Biosynthetic Process
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Acyl chain remodelling of PG
Drugs		Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Prostate cancer ( 23535732)	Major depressive disorder (unexposed to adversity) ( 29495898) Mean reticulocyte volume ( 32888494) Stearic acid (18:0) levels ( 23362303)
Interacting Genes		15 interacting genes: ANXA7 CD200R1L CDC42 CDKN1A GCH1 GON4L KCNJ9 LPGAT1 LSAMP PPM1D RALGAPA1 SMN1 TK1 TMPRSS7 TUFM	1 interacting genes: ATP6V1A
Entrez ID		523	9926
HPRD ID		06120	14304
Ensembl ID		ENSG00000114573	ENSG00000123684
Uniprot IDs		P38606	Q92604
PDB IDs		6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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