ATP6V1A and KCNJ9

		ATP6V1A	KCNJ9
Description		ATPase H+ transporting V1 subunit A	potassium inwardly rectifying channel subfamily J member 9
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GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Transport Vesicle Secretory Granule Intracellular Membrane-bounded Organelle Extracellular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Cellular Iron Ion Homeostasis ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Proton Transmembrane Transport	Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1	Ethanol Isavuconazole
Diseases
GWAS		Prostate cancer ( 23535732)	Alcohol consumption over the past year ( 29058377)
Interacting Genes		15 interacting genes: ANXA7 CD200R1L CDC42 CDKN1A GCH1 GON4L KCNJ9 LPGAT1 LSAMP PPM1D RALGAPA1 SMN1 TK1 TMPRSS7 TUFM	7 interacting genes: ADRB2 ATP6V1A DRD2 DRD4 KCNJ3 KCNJ6 TMEM201
Entrez ID		523	3765
HPRD ID		06120	02959
Ensembl ID		ENSG00000114573	ENSG00000162728
Uniprot IDs		P38606	Q92806
PDB IDs		6WLZ 6WM2 6WM3 6WM4	6X23
Enriched GO Terms of Interacting Partners?
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