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ATP6V1A

Description ATPase H+ transporting V1 subunit A
Image
GO Annotations Cellular Component
  • Vacuolar Proton-transporting V-type ATPase, V1 Domain
  • Nucleoplasm
  • Lysosomal Membrane
  • Cytosol
  • Plasma Membrane
  • Microvillus
  • Apical Plasma Membrane
  • Proton-transporting Two-sector ATPase Complex
  • Transport Vesicle
  • Secretory Granule
  • Intracellular Membrane-bounded Organelle
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • ATP Binding
  • Proton-transporting ATP Synthase Activity, Rotational Mechanism
  • Proton-transporting ATPase Activity, Rotational Mechanism
Biological Process
  • Cellular Iron Ion Homeostasis
  • ATP Synthesis Coupled Proton Transport
  • Regulation Of Macroautophagy
  • Cellular Response To Increased Oxygen Levels
  • Proton Transmembrane Transport
Pathways
  • ROS and RNS production in phagocytes
  • Insulin receptor recycling
  • Transferrin endocytosis and recycling
  • Amino acids regulate mTORC1
  • Ion channel transport
Drugs
  • Alendronic acid
  • Etidronic acid
  • Tiludronic acid
  • Bafilomycin A1
  • Bafilomycin B1
Diseases
GWAS
  • Prostate cancer ( 23535732)
Interacting Genes 15 interacting genes: ANXA7 CD200R1L CDC42 CDKN1A GCH1 GON4L KCNJ9 LPGAT1 LSAMP PPM1D RALGAPA1 SMN1 TK1 TMPRSS7 TUFM
Entrez ID 523
HPRD ID 06120
Ensembl ID ENSG00000114573
Uniprot IDs P38606
PDB IDs 6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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