TMPRSS7 and ATP6V1A

		TMPRSS7	ATP6V1A
Description		transmembrane serine protease 7	ATPase H+ transporting V1 subunit A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Transport Vesicle Secretory Granule Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	Protein Binding ATP Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Proteolysis	Cellular Iron Ion Homeostasis ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Cellular Response To Increased Oxygen Levels Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Telomere length ( 24478790)	Prostate cancer ( 23535732)
Interacting Genes		1 interacting genes: ATP6V1A	15 interacting genes: ANXA7 CD200R1L CDC42 CDKN1A GCH1 GON4L KCNJ9 LPGAT1 LSAMP PPM1D RALGAPA1 SMN1 TK1 TMPRSS7 TUFM
Entrez ID		344805	523
HPRD ID		19178	06120
Ensembl ID		ENSG00000176040	ENSG00000114573
Uniprot IDs		Q7RTY8	P38606
PDB IDs			6WLZ 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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