LNX2 and NAGK

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		LNX2	NAGK
Description		ligand of numb-protein X 2	N-acetylglucosamine kinase
Image
GO Annotations	Cellular Component		Cytosol Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity
	Biological Process	Protein Ubiquitination	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation
Pathways			Synthesis of UDP-N-acetyl-glucosamine
Drugs			N-Acetylglucosamine
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	34 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 ELP4 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82
Entrez ID		222484	55577
HPRD ID		10042	08441
Ensembl ID		ENSG00000139517	ENSG00000124357
Uniprot IDs		Q8N448	A0A384N6G7 C9JEV6 Q9UJ70
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22	2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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